Vezina Noemie, Al-Halabi Becher, Shash Hani, Dudley Roy R, Gilardino Mirko S
*Division of Plastic and Reconstructive Surgery, McGill University Health Centre, Montreal, QC, Canada†Department of Pediatric Surgery, Division of Neurosurgery, Montreal Children's Hospital, McGill University Health Centre, Montreal, QC, Canada.
J Craniofac Surg. 2017 May;28(3):604-609. doi: 10.1097/SCS.0000000000003379.
Growing skull fractures (GSFs) are rare complications of pediatric head trauma that comprise skull fractures associated with an underlying dural tear and an intact arachnoid membrane. They are often misdiagnosed, and delay in management can lead to progression of the disease along with its neurological sequelae. Multiple clinical reports and qualitative reviews on this entity exist. To our knowledge, this represents the largest clinical review reporting on established techniques in the management of these fractures.
A literature search was performed on the databases Embase, Medline, Cochrane, and PubMed from their inception until February 2015 using the terms "Growing," "Skull," "Fracture," and their equivalent terms. Studies included were case series with 5 or more patients describing GSFs and their management.
Twenty-two articles reporting 440 patients were included in the analysis. The mean age at trauma was 8.8 months, with the mean at presentation of 21.9 months and 57.8% of the patients being males. Most commonly, a combined dura-cranioplasty was done in 61.6% of the patients. A range of autoplastic and alloplastic materials were used in both of these techniques. Improvement from preoperative clinical status in seizures and neurological deficits was noted in 18 (12.7%) and 11 (7.05%) of the patients, respectively, following operative repair and medical management.
Early recognition is crucial in the management and treatment of GSF. Children at risk for developing GSF should be monitored clinically for up to 3 months following the initial insult. The surgical treatment depends on the size of the fracture and the age of the patient. A summary of the presentation, management, associated outcomes, complications, and recommendations discussed in the literature are reported within.
生长性颅骨骨折(GSFs)是小儿头部外伤的罕见并发症,包括与潜在硬脑膜撕裂和完整蛛网膜相关的颅骨骨折。它们常被误诊,治疗延迟会导致疾病进展及其神经后遗症。关于这一实体有多项临床报告和定性综述。据我们所知,这是关于这些骨折治疗中既定技术的最大规模临床综述报告。
在Embase、Medline、Cochrane和PubMed数据库中进行文献检索,检索时间从各数据库建立至2015年2月,使用的检索词为“生长性”“颅骨”“骨折”及其同义词。纳入的研究为病例系列,其中有5名或更多患者描述了生长性颅骨骨折及其治疗情况。
分析纳入了22篇报告440例患者的文章。受伤时的平均年龄为8.8个月,就诊时的平均年龄为21.9个月,57.8%的患者为男性。最常见的是,61.6%的患者进行了硬脑膜颅骨成形术联合手术。在这两种技术中都使用了多种自体材料和异体材料。手术修复和药物治疗后,分别有18例(12.7%)和11例(7.05%)患者的癫痫发作和神经功能缺损的术前临床状态得到改善。
早期识别在生长性颅骨骨折的管理和治疗中至关重要。有发生生长性颅骨骨折风险的儿童在初次受伤后应进行长达3个月的临床监测。手术治疗取决于骨折大小和患者年龄。本文报告了文献中讨论的临床表现、治疗、相关结果、并发症及建议的总结。