Zhao Danyang, Wang Yu, Han Dong
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639, Zhizaoju Road, Shanghai 200011, China.
Department of Geriatrics, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, No. 639, Zhizaoju Road, Shanghai 200011, China.
Biomed Res Int. 2016;2016:2075317. doi: 10.1155/2016/2075317. Epub 2016 Dec 18.
The treatment of bone defects is challenging and controversial. As a new technology, periosteal distraction osteogenesis (PDO) uses the osteogenicity of periosteum, which creates an artificial space between the bone surface and periosteum to generate new bone by gradually expanding the periosteum with no need for corticotomy. Using the newly formed bone of PDO to treat bone defects is effective, which can not only avoid the occurrence of immune-related complications, but also solve the problem of insufficient donor. This review elucidates the availability of PDO in the aspects of mechanisms, devices, strategies, and measures. Moreover, we also focus on the future prospects of PDO and hope that PDO will be applied to the clinical treatment of bone defects in the future.
骨缺损的治疗具有挑战性且存在争议。作为一项新技术，骨膜牵张成骨术（PDO）利用骨膜的成骨能力，在骨表面和骨膜之间制造一个人工空间，通过逐渐扩张骨膜来生成新骨，无需进行骨皮质切开术。利用PDO新形成的骨来治疗骨缺损是有效的，这不仅可以避免免疫相关并发症的发生，还能解决供体不足的问题。本综述阐明了PDO在机制、器械、策略和措施等方面的可行性。此外，我们还关注PDO的未来前景，希望PDO将来能应用于骨缺损的临床治疗。
