Department of Microbiology.
Department of Medicine, The University of Texas Health Science Center, Tyler, TX 75708.
Microbiol Spectr. 2017 Jan;5(1). doi: 10.1128/microbiolspec.TNMI7-0027-2016.
Rapidly growing mycobacteria (RGM) compose approximately one-half of the currently validated mycobacterial species and are divided into six major groups, including the Mycobacterium fortuitum group, M. chelonae/M. abscessus complex, M. smegmatis group, M. mucogenicum group, M. mageritense/M. wolinskyi, and the pigmented RGM. This review discusses each group and highlights the major types of infections associated with each group. Additionally, phenotypic and molecular laboratory identification methods, including gene sequencing, mass spectrometry, and the newly emerging whole-genome sequencing, are detailed, along with a discussion of the current antimicrobial susceptibility methods and patterns of the most common pathogenic species.
快速生长分枝杆菌(RGM)约占目前已验证分枝杆菌物种的一半,分为六个主要群,包括偶然分枝杆菌群、龟分枝杆菌/脓肿分枝杆菌复合群、耻垢分枝杆菌群、黏液分枝杆菌群、马杰里分枝杆菌/沃尔辛分枝杆菌,以及色素分枝杆菌。本文讨论了每个群,并强调了与每个群相关的主要感染类型。此外,还详细介绍了表型和分子实验室鉴定方法,包括基因测序、质谱和新兴的全基因组测序,并讨论了目前最常见的致病性物种的药敏方法和模式。