鼻窦及腹侧颅底恶性肿瘤的解剖学考量

Anatomic Considerations for Sinonasal and Ventral Skull Base Malignancy.

作者信息

Willson Thomas J, Fernandez-Miranda Juan C, Ferrareze Nunes Cristian, Lieber Stefan, Wang Eric W

机构信息

Department of Otolaryngology-Head & Neck Surgery, UPMC Eye & Ear Institute, University of Pittsburgh Medical Center, Suite 500, 203 Lothrop Street, Pittsburgh, PA 15213, USA.

Department of Neurological Surgery, UPMC Presbyterian, University of Pittsburgh Medical Center, Suite B-400, 200 Lothrop Street, Pittsburgh, PA 15213, USA.

出版信息

Otolaryngol Clin North Am. 2017 Apr;50(2):245-255. doi: 10.1016/j.otc.2016.12.003. Epub 2017 Jan 16.

DOI:10.1016/j.otc.2016.12.003

PMID:28104275

Abstract

Malignancies of the sinonasal region and ventral skull base include a varied group of uncommon tumors that are a challenge to treat. These malignancies, with few exceptions, often present late because of their insidious growth and bland symptomatology. As with malignancies of other sites, the primary goal in surgical management is complete resection with negative margins. This presents a unique surgical challenge in that these lesions lie within a region of densely populated anatomic real estate. This fact reinforces the importance of complete preoperative work-up and a sound anatomic understanding. This article discusses key anatomic regions and their importance from an endonasal perspective.

摘要

鼻窦区域和颅底腹侧的恶性肿瘤包括一组多样的罕见肿瘤，治疗颇具挑战。这些恶性肿瘤除少数例外，由于其隐匿性生长和症状不明显，往往就诊较晚。与其他部位的恶性肿瘤一样，手术治疗的主要目标是切缘阴性的完整切除。这带来了独特的手术挑战，因为这些病变位于解剖结构密集的区域。这一事实凸显了术前全面评估和扎实解剖学知识的重要性。本文从鼻内镜角度探讨关键解剖区域及其重要性。