Dumorné Kelly, Córdova David Camacho, Astorga-Eló Marcia, Renganathan Prabhaharan
Departamento de Ingeniería Química, Facultad de Ciencias Químicas y Recursos Naturales, Universidad de La Frontera, Chile.
Department of Pharmaceutical Sciences, Faculty of Pharmaceutical Sciences of Ribeirao Preto, University of Sao Paulo-USP, Brazil.
J Microbiol Biotechnol. 2017 Apr 28;27(4):649-659. doi: 10.4014/jmb.1611.11006.
Extremophilic microorganisms have established a diversity of molecular strategies in order to survive in extreme conditions. Biocatalysts isolated by these organisms are termed extremozymes, and possess extraordinary properties of salt allowance, thermostability, and cold adaptivity. Extremozymes are very resistant to extreme conditions owing to their great solidity, and they pose new opportunities for biocatalysis and biotransformations, as well as for the development of the economy and new line of research, through their application. Thermophilic proteins, piezophilic proteins, acidophilic proteins, and halophilic proteins have been studied during the last few years. Amylases, proteases, lipases, pullulanases, cellulases, chitinases, xylanases, pectinases, isomerases, esterases, and dehydrogenases have great potential application for biotechnology, such as in agricultural, chemical, biomedical, and biotechnological processes. The study of extremozymes and their main applications have emerged during recent years.
嗜极微生物已经建立了多种分子策略以便在极端条件下生存。由这些生物分离得到的生物催化剂被称为极端酶,它们具有耐盐、热稳定性和冷适应性等非凡特性。极端酶由于其高度稳定性而对极端条件具有很强的抗性,通过它们的应用,为生物催化和生物转化以及经济发展和新的研究领域带来了新机遇。在过去几年里,嗜热蛋白、嗜压蛋白、嗜酸蛋白和嗜盐蛋白都得到了研究。淀粉酶、蛋白酶、脂肪酶、支链淀粉酶、纤维素酶、几丁质酶、木聚糖酶、果胶酶、异构酶、酯酶和脱氢酶在生物技术领域,如农业、化学、生物医学和生物技术过程中具有巨大的潜在应用价值。近年来,对极端酶及其主要应用的研究不断涌现。