Department of Psychiatry and Human Behavior, Alpert Medical School of Brown University, Bradley Hospital, 1011 Veterans Memorial Parkway, East Providence, RI, 02915, USA.
J Abnorm Child Psychol. 2017 Nov;45(8):1577-1586. doi: 10.1007/s10802-017-0269-6.
A longstanding nosological question in the clinical literature is whether substance use disorders (SUDs) are best conceptualized as categorical or dimensional phenomena. Taxometric analysis is a statistical approach uniquely developed to address this issue. To date, no taxometric studies have been conducted with SUDs in adolescents. The current taxometric study investigated the latent structure of SUDs in adolescents for four different substances: marijuana, analgesics, hallucinogens, and inhalants. Interview-derived data for DSM-IV SUD symptoms were drawn from the National Survey on Drug Use and Health, pooled across the years 2004 to 2013 (unweighted n = 181,573; 48.92% female). Two mathematically non-redundant taxometric methods (MAMBAC [mean above minus below a cut] and MAXEIG [maximum eigenvalue]) were conducted with the data for respondents who had used the substance under study at least once in the past 12 months, or on 5 separate days in the case of marijuana (unweighted ns = 4900 to 17,517). Consistent evidence emerged in support of a dimensional solution across the analyses for all four substances (mean comparison curve fit index = 0.129 to 0.301). The current findings are consistent with the view of SUDs in adolescents as continuous syndromes rather than discrete entities. These findings are also consistent with theoretical conceptualizations of SUDs as having multi-causal etiologies, and have implications for current diagnostic conceptualizations of SUDs.
在临床文献中,一个长期存在的分类学问题是物质使用障碍(SUDs)是否最好被视为分类或维度现象。分类分析是一种专门用于解决这个问题的统计方法。迄今为止,尚未对青少年的 SUD 进行过分类分析研究。本研究采用分类分析方法,调查了青少年四种不同物质(大麻、阿片类药物、迷幻剂和吸入剂)的 SUD 潜在结构。DSM-IV SUD 症状的访谈数据来自国家药物使用和健康调查,汇总了 2004 年至 2013 年的数据(未加权 n=181573;女性占 48.92%)。对于过去 12 个月内至少使用过研究物质一次或在过去 12 个月内使用大麻 5 天以上的受访者的数据,采用两种数学上非冗余的分类分析方法(MAMBAC[均值大于下切分点减去下切分点]和 MAXEIG[最大特征值])进行分析(未加权 n 值为 4900 到 17517)。四项物质的分析结果均一致支持维度解决方案,平均比较曲线拟合指数为 0.129 到 0.301。目前的研究结果与将青少年 SUD 视为连续综合征而不是离散实体的观点一致。这些发现也与 SUD 多因病因理论概念一致,并对当前 SUD 的诊断概念化具有影响。