The effect of metal/fluoride complexes on fluoride uptake and caries-like lesion formation in enamel.

Pretreatment of enamel with TiCl3 and ZrOCL2-8H2O solutions prior to APF application was shown to increase fluoride uptake and reduce caries-like lesion formation to a greater extent than APF alone. The increase in fluoride uptake by enamel was not solely due to the low pH of the pretreatment solutions.