McBride Angela, Chau Tran Thi Hong, Hong Nguyen Thi Thu, Mai Nguyen Thi Hoang, Anh Nguyen To, Thanh Tran Tan, Van Tran Thi Hue, Xuan Le Thi, Sieu Tran Phu Manh, Thai Le Hong, Chuong Ly Van, Sinh Dinh Xuan, Phong Nguyen Duy, Phu Nguyen Hoan, Day Jeremy, Nghia Ho Dang Trung, Hien Tran Tinh, Chau Nguyen Van Vinh, Thwaites Guy, Tan Le Van
Oxford University Clinical Research Unit.
University College London Hospitals, United Kingdom.
Clin Infect Dis. 2017 Jun 15;64(12):1784-1787. doi: 10.1093/cid/cix118.
We utilized polymerase chain reaction (PCR) to demonstrate that Angiostrongylus cantonensis was responsible for 67.3% of 55 cases of eosinophilic meningitis from a cohort of 1,690 adult patients with CNS infection at a tertiary hospital in southern Vietnam. Longer duration of illness, depressed consciousness, and peripheral blood eosinophilia were associated with PCR positivity.
我们利用聚合酶链反应(PCR)来证明,在越南南部一家三级医院的1690名患有中枢神经系统感染的成年患者队列中,广州管圆线虫是55例嗜酸性粒细胞性脑膜炎病例中67.3%的病因。病程较长、意识障碍和外周血嗜酸性粒细胞增多与PCR阳性有关。