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子宫内膜癌患者因粒细胞集落刺激因子水平显著升高导致白细胞增多:病例报告及文献综述

Leukocytosis due to markedly elevated granulocyte-colony stimulating factor levels in a patient with endometrial cancer: Case report and literature review.

作者信息

Clark Leslie H, Moll Stephan, Houghton Damon, O'Connor Siohban, Soper John T

机构信息

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of North Carolina, United States.

Department of Medicine, Division of Hematology-Oncology, University of North Carolina School of Medicine, United States.

出版信息

Gynecol Oncol Rep. 2017 Jan 22;20:5-8. doi: 10.1016/j.gore.2017.01.007. eCollection 2017 May.

Abstract

•Granulocyte-colony stimulating factor (GCSF) secretion by gynecologic tumors is rare.•Elevations in serum GCSF can be seen in the absence of tumor GSCF secretion.•Extreme leukocytosis is associated with autocrine tumor growth and poor prognosis.

摘要

•妇科肿瘤分泌粒细胞集落刺激因子(GCSF)的情况很少见。

•在没有肿瘤GSCF分泌的情况下,血清GCSF也可能升高。

•极度白细胞增多与肿瘤自分泌生长及预后不良有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/58dc/5288325/8da6e8dcf1b6/gr1.jpg

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