麻醉期间的库尼斯综合征：惰性系统性肥大细胞增多症的表现：一例报告
Kounis Syndrome During Anesthesia: Presentation of Indolent Systemic Mastocytosis: A Case Report.
作者信息
de la Fuente Tornero Elena, Vega Castro Arantza, de Sierra Hernández Pedro Álvarez, Balaguer Recena Javier, Zaragoza Casares Sofía Carmen, Serrano Baylin Francisco Miguel, Gallardo Culebradas Paloma, Amorós Alfonso Beatriz, Rodríguez Fraile Jose Ramón
机构信息
From the Departments of *Anesthesiology, †Allergy, and §Cardiology, Hospital Universitario de Guadalajara, Castilla-La Mancha, Spain; ‡Department of Surgery, Hospital Universitario Quirónsalud Madrid, Madrid, Spain.
出版信息
A A Case Rep. 2017 May 1;8(9):226-228. doi: 10.1213/XAA.0000000000000474.
Mastocytosis comprises a heterogeneous group of disorders characterized by mast cell accumulation and proliferation in distinct organs. Kounis syndrome is defined as the concurrence of acute coronary syndromes with mast cell activation in a setting of allergic or hypersensitivity reactions. This is the first reported case of an intraoperative Kounis syndrome as the onset of an indolent systemic mastocytosis probably triggered by succinylated gelatin infusion during general anesthesia. The presentation of this case is intended to contribute to the knowledge of mastocytosis and Kounis syndrome at the time of diagnostic workup during intraoperative anaphylaxis or myocardial ischemia.
肥大细胞增多症是一组异质性疾病，其特征是肥大细胞在不同器官中积聚和增殖。库尼斯综合征定义为在过敏或超敏反应背景下，急性冠状动脉综合征与肥大细胞活化同时出现。这是首例报告的术中库尼斯综合征病例，惰性系统性肥大细胞增多症的发作可能是由全身麻醉期间输注琥珀酰明胶引发的。该病例的呈现旨在为术中过敏反应或心肌缺血诊断检查时的肥大细胞增多症和库尼斯综合征知识做出贡献。
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