Ozkan Derya, Gonen Emel, Akkaya Taylan, Bakir Mesut
Anesthesiology and Reanimation Department, Ministry of Health Diskapi Yildirim Beyazit Training and Research Hospital, Diskapi, 06110, Ankara, Turkey.
Orthopedics and Traumatology Department, Ministry of Health Diskapi Yildirim Beyazit Training and Research Hospital, Diskapi, 06110, Ankara, Turkey.
J Anesth. 2017 Jun;31(3):358-364. doi: 10.1007/s00540-017-2318-2. Epub 2017 Feb 14.
The aim of this study was to evaluate the effects of a preoperative popliteal block on sevoflurane consumption, postoperative pain, and analgesic consumption in children with cerebral palsy (CP) following lower limb surgery.
Fifty-four patients undergoing lower limb surgery were randomized to receive either a popliteal block + general anaesthesia (group P, n = 27) or general anaesthesia without a popliteal block (group C, n = 27). After anesthesia induction with 50% NO, O, and 8% sevoflurane, a popliteal block was given to group P patients with ultrasound guidance as a single dose of 0.3 ml/kg body weight of 0.25% bupivacaine. Group C patients received the same regimen of anesthesia induction but no preoperative popliteal block. Both the conductance fluctuation (SCF) peak numbers per second and the Wong-Baker FACES® Pain Rating Scale (WBFS) values of the patients were recorded upon arrival at the PACU, at 10 and 20 min after arrival at the PACU, and at postoperative hours 1, 4, 8, 12, and 24 when they were in the ward. The total paracetamol consumption of the patients was also recorded.
The end-tidal sevoflurane concentration values were significantly higher in group C patients than in group P patients, except for at 5 min after induction of anaesthesia (p < 0.001). The SCF peak numbers per second and WBFS scores were significantly higher in group C patients than in group P patients, except at Tp24h (p < 0.001). The total paracetamol consumption was 489.7 ± 122.7 mg in group P patients and 816.6 ± 166.5 in group C patients (p < 0.001).
Popliteal block is effective for postoperative analgesia, decreasing the paracetamol consumption and sevoflurane requirement in children with CP undergoing lower limb surgery. Trial registration ClinicalTrial.gov identifier: NCT02507700.
本研究旨在评估术前腘窝阻滞对脑瘫(CP)患儿下肢手术后七氟醚用量、术后疼痛及镇痛药物用量的影响。
54例行下肢手术的患者被随机分为两组,分别接受腘窝阻滞+全身麻醉(P组,n = 27)或单纯全身麻醉(C组,n = 27)。在使用50%氧化亚氮、氧气和8%七氟醚诱导麻醉后,P组患者在超声引导下接受腘窝阻滞,给予单剂量0.25%布比卡因0.3 ml/kg体重。C组患者接受相同的麻醉诱导方案,但未进行术前腘窝阻滞。记录患者到达麻醉后恢复室(PACU)时、到达PACU后10分钟和20分钟时、以及术后在病房的1、4、8、12和24小时的每秒电导波动(SCF)峰值数量和Wong-Baker面部表情疼痛评分量表(WBFS)值。还记录患者对乙酰氨基酚的总用量。
除麻醉诱导后5分钟外,C组患者的呼气末七氟醚浓度值显著高于P组患者(p < 0.001)。除术后24小时(Tp24h)外,C组患者的每秒SCF峰值数量和WBFS评分显著高于P组患者(p < 0.001)。P组患者对乙酰氨基酚的总用量为489.7 ± 122.7 mg,C组患者为816.6 ± 166.5 mg(p < 0.001)。
腘窝阻滞对术后镇痛有效,可减少CP患儿下肢手术后对乙酰氨基酚的用量和七氟醚的需求量。试验注册ClinicalTrial.gov标识符:NCT02507700。