McFarland S E, Mischke R H, Hopster-Iversen C, von Krueger X, Ammer H, Potschka H, Stürer A, Begemann K, Desel H, Greiner M
Department of Exposure, Federal Institute of Risk Assessment (BfR), Berlin, Germany.
Small Animal Clinic, University of Veterinary Medicine Hannover, Foundation, Hannover, Germany.
Vet Rec. 2017 Apr 1;180(13):327. doi: 10.1136/vr.103973. Epub 2017 Feb 24.
A systematic retrospective study on animal poisonings in Germany (wildlife excluded) between January 2012 and December 2015 was conducted. Data were collected on animal exposure calls to German poison centres, poisoning cases presenting to the University of Veterinary Medicine, Hannover Small Animal and Equine Clinics, cases involving off-label use of veterinary medicinal products reported to the Federal Office of Consumer Protection and Food Safety and toxicological submissions to the Institute of Pharmacology, Toxicology, and Pharmacy, Faculty of Veterinary Medicine, Ludwig-Maximilians-University, Munich. Descriptive statistics were used to characterise animal type, exposure reason, type and substance, year/month of exposure, case severity and outcome. An evaluation of the data and data sources was also carried out. Variation in poisoning patterns was seen. However, dogs and cats were the most frequently reported species and medicinal products, pesticides and plants were consistently implicated as top causes of poisoning. Advantages and disadvantages were associated with each data source; bias was found to be an important consideration when evaluating poisoning data. This study provided useful information on animal poisonings in Germany and highlights the need for standardised approaches for the collection, evaluation and integration of poisoning data from multiple sources.
对2012年1月至2015年12月期间德国(不包括野生动物)动物中毒情况进行了一项系统性回顾研究。收集了以下数据:德国中毒控制中心接到的动物接触毒物求助电话、汉诺威兽医学院小动物与马科动物诊所接收的中毒病例、向联邦消费者保护和食品安全办公室报告的涉及兽医药品超适应症使用的病例,以及向慕尼黑路德维希-马克西米利安大学兽医学院药理学、毒理学与药剂学研究所提交的毒理学报告。采用描述性统计方法对动物种类、接触毒物原因、毒物类型和物质、接触年份/月份、病例严重程度及结果进行了描述。同时还对数据及数据来源进行了评估。发现中毒模式存在差异。然而,犬类和猫类是报告最频繁的物种,药品、杀虫剂和植物一直是中毒的主要原因。每个数据来源都有其优缺点;在评估中毒数据时,偏倚是一个重要的考虑因素。本研究提供了有关德国动物中毒情况的有用信息,并强调需要采用标准化方法来收集、评估和整合来自多个来源的中毒数据。