Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, California.
Department of Radiation Oncology, Stanford University School of Medicine, Stanford, California.
Pract Radiat Oncol. 2017 Sep-Oct;7(5):311-318. doi: 10.1016/j.prro.2017.01.007. Epub 2017 Jan 19.
Radiation therapy is an important component of treatment for many childhood cancers. Depending upon the age and maturity of the child, pediatric radiation therapy often requires general anesthesia for immobilization, position reproducibility, and daily treatment delivery. We designed and clinically implemented a radiation therapy-compatible audiovisual system that allows children to watch streaming video during treatment, with the goal of reducing the need for daily anesthesia through immersion in video.
We designed an audiovisual-assisted therapeutic ambience in radiation therapy (AVATAR) system using a digital media player with wireless streaming and pico projector, and a radiolucent display screen positioned within the child's field of view to him or her with sufficient entertainment and distraction for the duration of serial treatments without the need for daily anesthesia. We piloted this system in 25 pediatric patients between the ages of 3 and 12 years. We calculated the number of fractions of radiation for which this system was used successfully and anesthesia avoided and compared it with the anesthesia rates reported in the literature for children of this age.
Twenty-three of 25 patients (92%) were able to complete the prescribed course of radiation therapy without anesthesia using the AVATAR system, with a total of 441 fractions of treatment administered when using AVATAR. The median age of patients successfully treated with this approach was 6 years. Seven of the 23 patients were initially treated with daily anesthesia and were successfully transitioned to use of the AVATAR system. Patients and families reported an improved treatment experience with the use of the AVATAR system compared with anesthesia.
The AVATAR system enables a high proportion of children to undergo radiation therapy without anesthesia compared with reported anesthesia rates, justifying continued development and clinical investigation of this technique.
放射治疗是许多儿童癌症治疗的重要组成部分。根据儿童的年龄和成熟度,儿科放射治疗通常需要全身麻醉以固定体位、保证体位重复性和每日治疗的实施。我们设计并临床实施了一种放射治疗兼容的视听系统,使儿童在治疗过程中可以观看流媒体视频,以期通过沉浸在视频中减少对每日麻醉的需求。
我们使用带有无线流媒体功能的数字媒体播放器和微投影仪以及置于儿童视野内的透光显示屏,设计了一种放射治疗中的视听辅助治疗环境(AVATAR)系统,为儿童提供足够的娱乐和分散注意力,使其能够在连续治疗期间完成治疗,而无需每日麻醉。我们在 25 名年龄在 3 至 12 岁的儿科患者中试用了该系统。我们计算了成功使用该系统并避免使用麻醉的放射治疗次数,并将其与该年龄段儿童的文献中报告的麻醉率进行比较。
25 名患者中有 23 名(92%)能够在没有麻醉的情况下成功完成规定的放射治疗疗程,共进行了 441 次治疗。成功接受该方法治疗的患者的中位年龄为 6 岁。23 名患者中有 7 名最初接受每日麻醉,并成功过渡到使用 AVATAR 系统。与使用麻醉相比,患者和家属报告说使用 AVATAR 系统可改善治疗体验。
与报告的麻醉率相比,AVATAR 系统使相当一部分儿童能够在无需麻醉的情况下接受放射治疗,这证明了该技术的持续开发和临床研究是合理的。