在丹麦猪群中发现了一种三重重组甲型流感病毒，其血凝素（H3）来源于人类季节性流感病毒，神经氨酸酶（NA）来源于猪流感病毒，内部基因来源于2009年甲型H1N1大流行病毒。
Triple-reassortant influenza A virus with H3 of human seasonal origin, NA of swine origin, and internal A(H1N1) pandemic 2009 genes is established in Danish pigs.
作者信息
Krog Jesper Schak, Hjulsager Charlotte Kristiane, Larsen Michael Albin, Larsen Lars Erik
机构信息
National Veterinary Institute, Technical University of Denmark, Frederiksberg C, Denmark.
Merial Norden A/S, Hørsholm, Denmark.
出版信息
Influenza Other Respir Viruses. 2017 May;11(3):298-303. doi: 10.1111/irv.12451. Epub 2017 Mar 21.
This report describes a triple-reassortant influenza A virus with a HA that resembles H3 of human seasonal influenza from 2004 to 2005, N2 from influenza A virus already established in swine, and the internal gene cassette from A(H1N1)pdm09 has spread in Danish pig herds. The virus has been detected in several Danish pig herds during the last 2-3 years and may possess a challenge for human as well as animal health.
本报告描述了一种三重重组甲型流感病毒，其血凝素（HA）类似于2004年至2005年人类季节性流感的H3，神经氨酸酶（N2）来自已在猪群中存在的甲型流感病毒，内部基因片段来自甲型H1N1流感大流行病毒（A(H1N1)pdm09），该病毒已在丹麦猪群中传播。在过去两到三年里，该病毒已在丹麦多个猪群中被检测到，可能对人类和动物健康构成威胁。
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