Suppr超能文献

使用因子混合模型评估异质性治疗样本中酒精使用障碍的A/B型分类

Using Factor Mixture Models to Evaluate the Type A/B Classification of Alcohol Use Disorders in a Heterogeneous Treatment Sample.

作者信息

Hildebrandt Tom, Epstein Elizabeth E, Sysko Robyn, Bux Donald A

机构信息

Department of Psychiatry, Mount Sinai School of Medicine, New York, New York.

Center of Alcohol Studies, Rutgers - The State University of New Jersey, Piscataway, New Jersey.

出版信息

Alcohol Clin Exp Res. 2017 May;41(5):987-997. doi: 10.1111/acer.13367. Epub 2017 Mar 30.

Abstract

BACKGROUND

The type A/B classification model for alcohol use disorders (AUDs) has received considerable empirical support. However, few studies examine the underlying latent structure of this subtyping model, which has been challenged as a dichotomization of a single drinking severity dimension. Type B, relative to type A, alcoholics represent those with early age of onset, greater familial risk, and worse outcomes from alcohol use.

METHODS

We examined the latent structure of the type A/B model using categorical, dimensional, and factor mixture models in a mixed-gender community treatment-seeking sample of adults with an AUD.

RESULTS

Factor analytic models identified 2 factors (drinking severity/externalizing psychopathology and internalizing psychopathology) underlying the type A/B indicators. A factor mixture model with 2 dimensions and 3 classes emerged as the best overall fitting model. The classes reflected a type A class and 2 type B classes (B1 and B2) that differed on the respective level of drinking severity/externalizing pathology and internalizing pathology. Type B1 had a greater prevalence of women and more internalizing pathology and B2 had a greater prevalence of men and more drinking severity/externalizing pathology. The 2-factor, 3-class model also exhibited predictive validity by explaining significant variance in 12-month drinking and drug use outcomes.

CONCLUSIONS

The model identified in this study may provide a basis for examining different sources of heterogeneity in the course and outcome of AUDs.

摘要

背景

酒精使用障碍(AUDs)的A/B型分类模型已获得大量实证支持。然而,很少有研究考察这种亚型分类模型的潜在潜在结构,该模型作为单一饮酒严重程度维度的二分法受到了挑战。相对于A型酗酒者,B型酗酒者代表那些发病年龄早、家族风险更高且饮酒后果更差的人。

方法

我们在一个寻求社区治疗的成年AUD患者的混合性别样本中,使用分类模型、维度模型和因子混合模型来考察A/B型模型的潜在结构。

结果

因子分析模型确定了A/B型指标背后的2个因子(饮酒严重程度/外化精神病理学和内化精神病理学)。一个具有2个维度和3个类别的因子混合模型成为总体拟合最佳的模型。这些类别反映了一个A型类别和2个B型类别(B1和B2),它们在饮酒严重程度/外化病理学和内化病理学的各自水平上有所不同。B1型女性患病率更高,内化病理学更多,而B2型男性患病率更高,饮酒严重程度/外化病理学更多。这个2因子、3类别模型通过解释12个月饮酒和药物使用结果中的显著方差,也表现出预测效度。

结论

本研究中确定的模型可能为检查AUDs病程和结果中不同的异质性来源提供基础。

相似文献

1
Using Factor Mixture Models to Evaluate the Type A/B Classification of Alcohol Use Disorders in a Heterogeneous Treatment Sample.
Alcohol Clin Exp Res. 2017 May;41(5):987-997. doi: 10.1111/acer.13367. Epub 2017 Mar 30.
2
Gender differences in the relationship of internalizing and externalizing psychopathology to alcohol dependence: likelihood, expression and course.
Drug Alcohol Depend. 2010 Nov 1;112(1-2):9-17. doi: 10.1016/j.drugalcdep.2010.04.019. Epub 2010 Jun 16.
3
Dynamic Features of Problematic Drinking: Alcohol Use Disorder Latent Classes Across Ages 18-64.
Alcohol Alcohol. 2019 Jan 1;54(1):97-103. doi: 10.1093/alcalc/agy074.
4
Internalizing and externalizing subtypes of alcohol misuse and their relation to drinking motives.
Addict Behav. 2023 Jan;136:107461. doi: 10.1016/j.addbeh.2022.107461. Epub 2022 Aug 27.
7
Using a factor mixture modeling approach in alcohol dependence in a general population sample.
Drug Alcohol Depend. 2008 Nov 1;98(1-2):105-14. doi: 10.1016/j.drugalcdep.2008.04.018. Epub 2008 Jun 30.
8
Characterization of South African adolescents with alcohol use disorders but without psychiatric or polysubstance comorbidity.
Alcohol Clin Exp Res. 2011 Sep;35(9):1705-15. doi: 10.1111/j.1530-0277.2011.01517.x. Epub 2011 Apr 27.
9
DSM-5 Latent Classes of Alcohol Users among Treatment Seeking Older Adults.
Subst Use Misuse. 2020;55(8):1214-1222. doi: 10.1080/10826084.2020.1731546. Epub 2020 Feb 28.
10
Reward and relief craving tendencies in patients with alcohol use disorders: results from the PREDICT study.
Addict Behav. 2013 Feb;38(2):1532-1540. doi: 10.1016/j.addbeh.2012.06.018. Epub 2012 Jun 26.

引用本文的文献

1
Drinking Motives, Alcohol Misuse, and Internalizing and Externalizing Psychopathology across College: A Cross-Lagged Panel Study.
Subst Use Misuse. 2023;58(11):1377-1387. doi: 10.1080/10826084.2023.2223269. Epub 2023 Jun 20.
2
Punch-Drunk or Drunken Boxing? The Etiology of Alcohol-Related Physical Violence through Adolescence and Young Adulthood.
Subst Use Misuse. 2021;56(5):615-626. doi: 10.1080/10826084.2021.1887244. Epub 2021 Mar 10.
3

本文引用的文献

1
Gender and Alcoholic Subtypes.
Alcohol Health Res World. 1996;20(1):56-62.
4
Distinguishing Between Latent Classes and Continuous Factors: Resolution by Maximum Likelihood?
Multivariate Behav Res. 2006 Dec 1;41(4):499-532. doi: 10.1207/s15327906mbr4104_4.
5
Commonalities and Differences Across Substance Use Disorders: Phenomenological and Epidemiological Aspects.
Alcohol Clin Exp Res. 2015 Oct;39(10):1878-900. doi: 10.1111/acer.12838. Epub 2015 Sep 1.
6
Transdiagnostic factors of psychopathology and substance use disorders: a review.
Soc Psychiatry Psychiatr Epidemiol. 2015 Feb;50(2):171-82. doi: 10.1007/s00127-014-1001-2. Epub 2015 Jan 7.
7
A test of the DSM-5 severity scale for alcohol use disorder.
Drug Alcohol Depend. 2014 Aug 1;141:39-43. doi: 10.1016/j.drugalcdep.2014.05.004. Epub 2014 May 17.
8
Applicability of Type A/B alcohol dependence in the general population.
Drug Alcohol Depend. 2014 May 1;138:169-76. doi: 10.1016/j.drugalcdep.2014.02.698. Epub 2014 Mar 5.
10
Empirical derived AUD sub types in the US general population: a latent class analysis.
Addict Behav. 2013 Nov;38(11):2782-6. doi: 10.1016/j.addbeh.2013.06.022. Epub 2013 Jul 11.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验