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室温下使用He矢量光泵磁力仪进行的磁心动图测量。

Magnetocardiography measurements with He vector optically pumped magnetometers at room temperature.

作者信息

Morales S, Corsi M C, Fourcault W, Bertrand F, Cauffet G, Gobbo C, Alcouffe F, Lenouvel F, Le Prado M, Berger F, Vanzetto G, Labyt E

机构信息

CEA, LETI, MINATEC Campus, F-38054 Grenoble, France.

出版信息

Phys Med Biol. 2017 Aug 21;62(18):7267-7279. doi: 10.1088/1361-6560/aa6459.

Abstract

In this paper, we present a proof of concept study which demonstrates for the first time the possibility of recording magnetocardiography (MCG) signals with He vector optically pumped magnetometers (OPM) operated in a gradiometer mode. Resulting from a compromise between sensitivity, size and operability in a clinical environment, the developed magnetometers are based on the parametric resonance of helium in a zero magnetic field. Sensors are operated at room temperature and provide a tri-axis vector measurement of the magnetic field. Measured sensitivity is around 210 f T (√Hz) in the bandwidth (2 Hz; 300 Hz). MCG signals from a phantom and two healthy subjects are successfully recorded. Human MCG data obtained with the OPMs are compared to reference electrocardiogram recordings: similar heart rates, shapes of the main patterns of the cardiac cycle (P/T waves, QRS complex) and QRS widths are obtained with both techniques.

摘要

在本文中,我们展示了一项概念验证研究,首次证明了使用梯度计模式下的氦矢量光泵磁力计(OPM)记录心磁图(MCG)信号的可能性。由于在临床环境中的灵敏度、尺寸和可操作性之间的折衷,所开发的磁力计基于零磁场中氦的参量共振。传感器在室温下运行,并提供磁场的三轴矢量测量。在带宽(2赫兹;300赫兹)内测得的灵敏度约为210飞特斯拉(√赫兹)。成功记录了来自模型和两名健康受试者的MCG信号。将使用OPM获得的人体MCG数据与参考心电图记录进行比较:两种技术获得的心率、心动周期主要模式(P/T波、QRS复合波)的形状和QRS宽度相似。

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