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经微导管直接经皮穿刺并释放线圈后,对下颌动静脉畸形进行无水乙醇栓塞术

Absolute Ethanol Embolisation of Mandibular Arteriovenous Malformations Following Direct Percutaneous Puncture and Release of Coils via a Microcatheter.

作者信息

Wang D, Su L, Han Y, Wang Z, Zheng L, Fan X

机构信息

Department of Interventional Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China; Department of Oral and Maxillofacial Surgery, First Affiliated Hospital and Faculty of Dentistry, Harbin Medical University, No. 23 Youzheng Street, Harbin, PR China.

Department of Interventional Radiology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.

出版信息

Eur J Vasc Endovasc Surg. 2017 Jun;53(6):862-869. doi: 10.1016/j.ejvs.2017.01.022. Epub 2017 Mar 7.

Abstract

OBJECTIVE/BACKGROUND: To evaluate the safety, efficacy, and medium-term outcome of a modified technique of ethanol embolisation of mandibular arteriovenous malformations (AVMs) following a direct percutaneous transvenous approach to the release of coils via a microcatheter.

METHODS

From January 2012 to July 2014, 18 consecutive patients (mean age 20.9 years [range 10-35 years]) with symptomatic AVMs of the mandible were enrolled. A microcatheter was inserted into the lesion via a direct percutaneous puncture needle. Electrolytically detachable coils and 0.018 mm coils were super-selectively placed to decrease the flow and volume of the arteriovenous fistulas via a microcatheter. Absolute ethanol was injected to obliterate the fistulas. Clinical follow-up was performed in all patients. Therapeutic outcomes were determined by evaluating the degree of devascularisation at follow-up angiography and symptoms and signs.

RESULTS

Transvenous release of coils combined with absolute ethanol embolisation were used in all cases. The amount of ethanol used ranged from 5 to 50 mL (mean 25.7 mL) in a single session. Sixteen of 18 patients were cured, and two had partial remission. Follow-up times ranged from 8 to 26 months (medium 15.7 months), and there was no angiographic recurrence of the lesions. Minor complication occurred in five of the 18 patients. There were no major complications.

CONCLUSION

Absolute ethanol embolisation following a direct percutaneous transvenous approach to release coils via a microcatheter is a feasible, safe, and highly effective method for the management of mandibular AVMs.

摘要

目的/背景:通过微导管经皮直接经静脉途径释放线圈后,评估改良乙醇栓塞下颌动静脉畸形(AVM)技术的安全性、有效性及中期疗效。

方法

2012年1月至2014年7月,连续纳入18例有症状的下颌骨AVM患者(平均年龄20.9岁[范围10 - 35岁])。通过直接经皮穿刺针将微导管插入病变部位。通过微导管超选择性放置电解可脱卸线圈和0.018 mm线圈,以减少动静脉瘘的血流和体积。注入无水乙醇闭塞瘘管。对所有患者进行临床随访。通过随访血管造影评估血管减少程度以及症状和体征来确定治疗效果。

结果

所有病例均采用经静脉释放线圈联合无水乙醇栓塞。单次治疗中使用的乙醇量为5至50 mL(平均25.7 mL)。18例患者中有16例治愈,2例部分缓解。随访时间为8至26个月(中位时间15.7个月),病变无血管造影复发。18例患者中有5例出现轻微并发症。无严重并发症。

结论

经皮直接经静脉途径通过微导管释放线圈后进行无水乙醇栓塞是治疗下颌骨AVM的一种可行、安全且高效的方法。

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