Coughlin Steven, Peyerl Fred W, Munson Sibyl H, Ravindranath Aditi J, Lee-Chiong Teofilo L
Philips Respironics, Murrysville, PA, USA.
Boston Strategic Partners, Inc., Boston, MA, USA.
Value Health. 2017 Mar;20(3):379-387. doi: 10.1016/j.jval.2016.09.2401. Epub 2016 Nov 11.
Although evidence suggests significant clinical benefits of home noninvasive ventilation (NIV) for management of severe chronic obstructive pulmonary disease (COPD), economic analyses supporting the use of this technology are lacking.
To evaluate the economic impact of adopting home NIV, as part of a multifaceted intervention program, for severe COPD.
An economic model was developed to calculate savings associated with the use of Advanced NIV (averaged volume assured pressure support with autoexpiratory positive airway pressure; Trilogy100, Philips Respironics, Inc., Murrysville, PA) versus either no NIV or a respiratory assist device with bilevel pressure capacity in patients with severe COPD from two distinct perspectives: the hospital and the payer. The model examined hospital savings over 90 days and payer savings over 3 years. The number of patients with severe COPD eligible for home Advanced NIV was user-defined. Clinical and cost data were obtained from a quality improvement program and published reports. Scenario analyses calculated savings for hospitals and payers covering different COPD patient cohort sizes.
The hospital base case (250 patients) revealed cumulative savings of $402,981 and $449,101 over 30 and 90 days, respectively, for Advanced NIV versus both comparators. For the payer base case (100,000 patients), 3-year cumulative savings with Advanced NIV were $326 million versus no NIV and $1.04 billion versus respiratory assist device.
This model concluded that adoption of home Advanced NIV with averaged volume assured pressure support with autoexpiratory positive airway pressure, as part of a multifaceted intervention program, presents an opportunity for hospitals to reduce COPD readmission-related costs and for payers to reduce costs associated with managing patients with severe COPD on the basis of reduced admissions.
尽管有证据表明家庭无创通气(NIV)对重度慢性阻塞性肺疾病(COPD)的管理具有显著的临床益处,但支持使用该技术的经济分析却很缺乏。
评估将家庭NIV作为多方面干预计划的一部分用于重度COPD的经济影响。
开发了一个经济模型,从医院和支付方两个不同角度计算在重度COPD患者中使用高级NIV(平均容量保证压力支持加自动呼气末正压;飞利浦伟康公司的Trilogy100,宾夕法尼亚州默里斯维尔)与不使用NIV或使用具有双水平压力功能的呼吸辅助设备相比所节省的费用。该模型考察了90天内医院节省的费用以及3年内支付方节省的费用。符合家庭高级NIV条件的重度COPD患者数量由用户定义。临床和成本数据来自一项质量改进计划及已发表的报告。情景分析计算了涵盖不同COPD患者队列规模的医院和支付方的节省费用情况。
医院基本情况(250例患者)显示,与两种对照相比,高级NIV在30天和90天分别累计节省402,981美元和449,101美元。对于支付方基本情况(100,000例患者),使用高级NIV 3年累计节省3.26亿美元(与不使用NIV相比)和10.4亿美元(与呼吸辅助设备相比)。
该模型得出结论,作为多方面干预计划的一部分,采用具有平均容量保证压力支持加自动呼气末正压的家庭高级NIV,为医院降低与COPD再入院相关的成本以及支付方基于减少入院人数降低管理重度COPD患者的成本提供了机会。