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[因意外动脉内注射氟氯西林导致手部坏疽:病例报告]

[Gangrene of the hand due to accidental intra-arterial injection of floxacilline: about a case].

作者信息

Salama Tarik, Aghoutane El Mohtadi, Fezzazi Rédouane El

机构信息

Service de Chirurgie Pédiatrique A, Départment des maladies de L'Enfant, CHU Mohammed VI, Université Cadi Ayyad, Marrakech, Maroc.

出版信息

Pan Afr Med J. 2016 Dec 6;25:221. doi: 10.11604/pamj.2016.25.221.10803. eCollection 2016.

Abstract

Floxacilline is a beta-lactam antibiotic of the penicillin class. In our context it is used to fight against infections caused by gram-positive bacteria, including staphylococcus aureus. However, floxacilline should be administered with great caution due to its possible side-effects. Our study reports the case of a 6-year old boy who underwent surgery for the treatment of a humeral fracture. The child was treated with injectable floxacilline following a suspected orthopaedic device infection 2 months after surgery. The day after starting antibiotic treatment, the child presented with acute ischemia of the right hand. Then, he was referred to us. Explorations objectified occlusion of the radial artery. The patient underwent relieving fasciotomy and received postoperative heparin. The evolution was marked by gangrene affecting the whole hand. The aim of our study was to educate caregivers about the risk of occurrence of this disastrous complication and about the measures to prevent it.

摘要

氟氯西林是一种青霉素类的β-内酰胺抗生素。在我们的情况中,它用于对抗革兰氏阳性菌引起的感染,包括金黄色葡萄球菌。然而,由于其可能的副作用,氟氯西林的使用应极为谨慎。我们的研究报告了一名6岁男孩的病例,该男孩接受了肱骨骨折治疗手术。术后2个月,因疑似骨科器械感染,该患儿接受了注射用氟氯西林治疗。开始抗生素治疗后的第二天,患儿出现右手急性缺血。随后,他被转诊至我们这里。检查发现桡动脉闭塞。患者接受了减压筋膜切开术,并在术后接受了肝素治疗。病情发展以整个手部坏疽为特征。我们研究的目的是让护理人员了解这种灾难性并发症发生的风险以及预防措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/010f/5337270/021d951b061b/PAMJ-25-221-g001.jpg

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