Polemikos Manolis, Heissler Hans E, Hermann Elvis J, Krauss Joachim K
Department of Neurosurgery, Hannover Medical School, Hannover, Germany.
Department of Neurosurgery, Hannover Medical School, Hannover, Germany.
World Neurosurg. 2017 May;101:814.e11-814.e14. doi: 10.1016/j.wneu.2017.03.004. Epub 2017 Mar 12.
Familial cases of idiopathic intracranial hypertension (IIH) are exceedingly rare, and its occurrence in monozygotic twins has not been reported previously.
We report monozygotic female twins who developed IIH, one at age 25 years and the other at age 28 years. Continuous intracranial pressure (ICP) monitoring confirmed elevated ICP as measured initially by lumbar puncture. In both cases, successful treatment with resolution of papilledema and symptoms relief was achieved after ventriculoperitoneal shunting.
This report documents the first case of IIH in monozygotic twins and the associated changes in ICP dynamics. Interestingly, almost equivalent alterations in ICP dynamics were found in the 2 patients.
特发性颅内高压（IIH）的家族性病例极为罕见，此前尚未有其在单卵双胞胎中发生的报道。
我们报告了一对患IIH的单卵双胞胎女性，其中一人发病年龄为25岁，另一人为28岁。持续颅内压（ICP）监测证实最初通过腰椎穿刺测得的ICP升高。在这两例病例中，脑室腹腔分流术后成功治愈，视乳头水肿消退且症状缓解。
本报告记录了首例单卵双胞胎患IIH的病例以及相关的ICP动态变化。有趣的是，在这两名患者中发现了几乎相同的ICP动态变化。
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