Vargas-Laguna Elena, Imbernón-Moya Adrián, Aguilar-Martínez Antonio, Burgos Fernando
Department of Dermatology, Hospital Universitario Severo Ochoa, Avenida de Orellana, Leganés, 28911 Madrid, Spain.
Department of Pathology, Hospital Universitario Severo Ochoa, Avenida de Orellana, Leganés, 28911 Madrid, Spain.
Case Rep Dermatol Med. 2017;2017:3613109. doi: 10.1155/2017/3613109. Epub 2017 Feb 23.
Warty dyskeratoma is an uncommon entity characterized by a solitary keratotic papule or nodule usually located in the head and neck of young adults. The histopathology shows a pattern of acantholytic dyskeratosis. We report a 32-year-old man who presented pain, serous exudation, a distal onycholysis with subungual hyperkeratosis, and roundish erythronychia in the nail plate of his left first toe 2 years ago. A histopathologic diagnosis of subungual warty dyskeratoma was made. When dealing with focal acantholytic dyskeratosis several differential diagnoses should be considered including Darier's disease, transient focal acantholytic dyskeratosis or Grover disease, and Hailey-Hailey disease. We present an unusual location of warty dyskeratoma in the nail bed using a clinicohistopathological correlation for the diagnosis.
疣状角化不良瘤是一种罕见的疾病,其特征为单个角化性丘疹或结节,通常位于年轻人的头颈部。组织病理学表现为棘层松解性角化不良的模式。我们报告一名32岁男性,2年前其左足第一趾甲出现疼痛、浆液性渗出、远端甲剥离伴甲下角化过度以及甲板上的圆形红甲。作出了甲下疣状角化不良瘤的组织病理学诊断。在处理局灶性棘层松解性角化不良时,应考虑多种鉴别诊断,包括达里埃病、暂时性局灶性棘层松解性角化不良或格罗弗病以及黑利-黑利病。我们通过临床组织病理学相关性诊断,展示了疣状角化不良瘤在甲床的不寻常位置。