Vieira René Aloisio da Costa, da Silva Katia Mathias Teixeira, de Oliveira-Junior Idam, de Lima Marcos Alves
Postgraduate Program in Oncology, Barretos Cancer Hospital, Pio XII Foundation, Barretos, São Paulo, Brazil.
Department of Mastology and Breast Reconstruction, Barretos Cancer Hospital, Pio XII Foundation, Barretos, São Paulo, Brazil.
J Surg Oncol. 2017 Jun;115(8):949-958. doi: 10.1002/jso.24619. Epub 2017 Mar 27.
Locally advanced breast cancer (LABC) is still a common problem in developing countries. Extensive resections are aimed at local control and improving quality of life. Dermofat flaps are an option for medium-sized defects.
Evaluate the results of a new thoracoabdominal flap (TAF).
We describe and evaluate an ipsilateral, thoracoabdominal horizontal, dermofat (ITADE) flap performed in patients submitted to mastectomy and immediate reconstruction. A systematic review of the flaps used in this situation was performed.
A total of 23 patients underwent the ITADE flap. The average flap size was 360 cm . One (4.3%) patient presented extensive loss of the flap. In the literature review, we observed 354 patients with 159 TAFs. We added our cases to the evaluation. A significant reduction in the risk of necrosis using myocutaneous flaps versus TAFs was observed (P < 0.001). Comparing other TAFs and ITADE flaps, considering all necrosis, a significant difference was apparent (P = 0.02), which disappeared when evaluating only larger necrosis (P = 0.13). Multivariate analysis showed that the resected area was the best variable related to the presence of necrosis.
ITADE allows extensive coverage areas, an early start of adjuvant treatment and it can be performed without requiring a reconstructive team.
局部晚期乳腺癌(LABC)在发展中国家仍是一个常见问题。广泛切除旨在实现局部控制并改善生活质量。真皮脂肪瓣是中型缺损的一种选择。
评估一种新的胸腹皮瓣(TAF)的效果。
我们描述并评估了在接受乳房切除术和即刻重建的患者中实施的同侧胸腹水平真皮脂肪(ITADE)皮瓣。对这种情况下使用的皮瓣进行了系统评价。
共有23例患者接受了ITADE皮瓣手术。皮瓣平均大小为360平方厘米。1例(4.3%)患者出现皮瓣大面积坏死。在文献综述中,我们观察到354例患者使用了159个TAF。我们将我们的病例纳入评估。观察到使用肌皮瓣与TAF相比坏死风险显著降低(P < 0.001)。比较其他TAF和ITADE皮瓣,考虑所有坏死情况,有显著差异(P = 0.02),仅评估较大面积坏死时差异消失(P = 0.13)。多变量分析表明,切除面积是与坏死存在相关的最佳变量。
ITADE皮瓣可提供广泛的覆盖面积,能尽早开始辅助治疗,且无需重建团队即可实施。