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波兰东南部城乡糖尿病性黄斑水肿患者的阈下微脉冲577纳米黄色激光治疗

Subthreshold micropulse yellow 577 nm laser therapy of diabetic macular oedema in rural and urban patients of south-eastern Poland.

作者信息

Latalska Małgorzata, Prokopiuk Agata, Wróbel-Dudzińska Dominika, Mackiewicz Jerzy

机构信息

Department of Diagnostics and Microsurgery of Glaucoma, Medical University, Lublin.

Department of Vitreoretinal Surgery, Medical University, Lublin.

出版信息

Ann Agric Environ Med. 2017 Mar 21;24(1):96-99. doi: 10.5604/12321966.1233899.

Abstract

UNLABELLED

Objectiv. To evaluate the efficacy of subthreshold micropulse yellow (577 nm) laser photocoagulation in diffuse macular edema (DME) in rural and urban patients of south-eastern Poland.

MATERIALS AND METHOD

Seventy-five eyes of 75 patients with diffuse DME were treated with subthreshold micropulse yellow laser photocoagulation with a 5% duty cycle at an energy level. The laser exposure time was 20 ms and the spot diameter was 100 μm. Best corrected visual acuity (BCVA), reading vision (Snellen) and optical coherence tomography-determined central retinal thickness (CRT) were estimated before and 2, 4 and 6 months after laser treatment. There were no statistically important differences in: the advancement of DME, HbA1c (glycated hemoglobin) level, duration of diabetes mellitus (DM), the degree of vision damage between rural and urban patients.

RESULTS

The follow-up was 6 months later. The baseline BCVA was 0.20 and remained stable- 0.3 after 6 months. The Snellen at baseline was 1.0 and improved to 0.5 finally (p=0.0004). The CRT at baseline was 500 μm and changed to 346 μm (p=0.00000) at the final follow-up. Finally, no retinal damage was observed.

CONCLUSIONS

Place of residence had no statistically significant effect on the demographics data, baseline visual acuity, reading visual acuity and central retinal thickness. Subthreshold micropulse yellow laser showed a highly significant efficiency in the treatment of DME. The effects of the treatment were more significant in rural patients than in urban ones.

摘要

未标注

目的。评估阈下微脉冲黄光(577纳米)激光光凝术对波兰东南部农村和城市弥漫性黄斑水肿(DME)患者的疗效。

材料与方法

75例弥漫性DME患者的75只眼睛接受了能量水平为5%占空比的阈下微脉冲黄光激光光凝术治疗。激光曝光时间为20毫秒,光斑直径为100微米。在激光治疗前以及治疗后2、4和6个月评估最佳矫正视力(BCVA)、阅读视力(斯内伦视力表)和光学相干断层扫描测定的中心视网膜厚度(CRT)。农村和城市患者在以下方面无统计学上的显著差异:DME的进展、糖化血红蛋白(HbA1c)水平、糖尿病(DM)病程、视力损害程度。

结果

随访6个月后。基线BCVA为0.20,6个月后保持稳定——为0.3。基线时的斯内伦视力表读数为1.0,最终提高到0.5(p = 0.0004)。基线CRT为500微米,最终随访时变为346微米(p = 0.00000)。最后,未观察到视网膜损伤。

结论

居住地点对人口统计学数据、基线视力、阅读视力和中心视网膜厚度无统计学上的显著影响。阈下微脉冲黄光激光在治疗DME方面显示出高度显著的疗效。该治疗对农村患者的效果比对城市患者更显著。

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