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终末期肾病患者的急诊透析通路:需要改进之处

Incident Dialysis Access in Patients With End-Stage Kidney Disease: What Needs to Be Improved.

作者信息

Moist Louise M, Lok Charmaine E

机构信息

Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Kidney Clinical Research Unit, London Health Sciences Centre, London, Ontario, Canada.

Department of Medicine, University Health Network, Toronto, Ontario, Canada; University of Toronto, Toronto, Ontario, Canada.

出版信息

Semin Nephrol. 2017 Mar;37(2):151-158. doi: 10.1016/j.semnephrol.2016.12.005.

Abstract

The initiation of dialysis is a challenging time of transition for patients, families, and their supporters. Patients with exposure to a comprehensive chronic kidney disease clinic may have had education and subsequent decision making regarding dialysis modality and access; however, many patients with or without prior education will require an urgent start to dialysis, requiring quick decisions regarding dialysis modality and access. In many countries, hemodialysis (HD) using a central venous catheter (CVC) is the most common initial renal replacement modality and dialysis access. Multiple factors, both remedial and nonremedial, contribute to this including late referral, rapid decrease in kidney function, delay in delivery or acceptance of education, and decision making and other system delays. Recent use of urgent peritoneal dialysis as the initial dialysis modality has resulted in decreased exposure to CVCs and in-center HD. This article addresses the current state of incident dialysis access, recent trends toward urgent peritoneal dialysis start, and opportunities to avoid the use of CVCs for HD when appropriate, with a focus on considering dialysis access as a critical component of the end-stage kidney disease life-plan, which requires consideration of future modalities and access when making the choice of the initial dialysis access.

摘要

对患者、家属及其支持者来说,开始透析是一个充满挑战的过渡时期。接触过综合慢性肾脏病诊所的患者可能已经接受了关于透析方式和通路的教育并做出了后续决策;然而,许多接受过或未接受过前期教育的患者都需要紧急开始透析,这就需要快速做出关于透析方式和通路的决策。在许多国家,使用中心静脉导管(CVC)进行血液透析(HD)是最常见的初始肾脏替代方式和透析通路。多种因素,包括可补救和不可补救的因素,都导致了这种情况,其中包括转诊延迟、肾功能快速下降、教育交付或接受延迟、决策及其他系统延迟。近期将紧急腹膜透析作为初始透析方式的应用已减少了CVC的使用及中心血液透析。本文阐述了新发透析通路的现状、紧急开始腹膜透析的近期趋势,以及在适当情况下避免将CVC用于血液透析的机会,重点是将透析通路视为终末期肾病生活规划的关键组成部分,这在选择初始透析通路时需要考虑未来的方式和通路。

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