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红色在与氧化应激相关的慢性疾病中的意义。

Implications of red in oxidative stress associated chronic diseases.

作者信息

Lee Yoon-Mi, Yoon Haelim, Park Hyun-Min, Song Byeng Chun, Yeum Kyung-Jin

机构信息

Division of Food Bioscience, College of Biomedical and Health Sciences, Konkuk University, Chungju, Korea.

出版信息

J Ginseng Res. 2017 Apr;41(2):113-119. doi: 10.1016/j.jgr.2016.03.003. Epub 2016 Mar 10.

Abstract

The steaming process of has been reported to increase its major known bioactive components, ginsenosides, and, therefore, its biological properties as compared to regular Biological functions of red attenuating pro-oxidant environments associated with chronic diseases are of particular interest, since oxidative stress can be a key contributor to the pathogenesis of chronic diseases. Additionally, proper utilization of various biomarkers for evaluating antioxidant activities in natural products, such as ginseng, can also be important to providing validity to their activities. Thus, studies on the effects of red ginseng against various diseases as determined in cell lines, animal models, and humans were reviewed, along with applied biomarkers for verifying such effects. Limitations and future considerations of studying red ginseng were been discussed. Although further clinical studies are warranted, red ginseng appears to be beneficial for attenuating disease-associated symptoms via its antioxidant activities, as well as for preventing oxidative stress-associated chronic diseases.

摘要

据报道, 的蒸煮过程会增加其主要已知生物活性成分人参皂苷,因此与普通 相比,其生物学特性也有所增强。红 的生物功能,尤其是减轻与慢性疾病相关的促氧化环境,这一点特别受关注,因为氧化应激可能是慢性疾病发病机制的关键因素。此外,合理利用各种生物标志物来评估天然产物(如人参)中的抗氧化活性,对于验证其活性的有效性也很重要。因此,本文综述了红参在细胞系、动物模型和人体中对各种疾病影响的研究,以及用于验证这些影响的应用生物标志物。还讨论了研究红参的局限性和未来的考虑因素。尽管有必要进行进一步的临床研究,但红参似乎通过其抗氧化活性对减轻疾病相关症状有益,同时也有助于预防与氧化应激相关的慢性疾病。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/18f5/5386131/a6407cb9ae06/gr1.jpg

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