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多囊卵巢综合征女性的营养管理:一项综述研究。

Nutritional management in women with polycystic ovary syndrome: A review study.

作者信息

Faghfoori Zeinab, Fazelian Siavash, Shadnoush Mahdi, Goodarzi Reza

机构信息

Food (Salt) Safety Research Center, School of Nutrition and Food Sciences, Semnan University of Medical Sciences, Semnan, Iran.

Songhor Healthcare Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

出版信息

Diabetes Metab Syndr. 2017 Nov;11 Suppl 1:S429-S432. doi: 10.1016/j.dsx.2017.03.030. Epub 2017 Apr 5.

Abstract

Polycystic ovary syndrome (PCOS) is endocrine disorder in women of reproductive age, which leads to reproductive, hormonal and metabolic abnormalities. Due to the presence of insulin resistance, PCOS increases the risk of chronic diseases like type 2 diabetes, hypertension, lipid disorders, cardiovascular diseases and malignancies such as breast and endometrial cancer. The actual cause of this syndrome is unknown but environmental factors such as dietary habits play an important role in prevention and treatment and lifestyle modifications are the most important therapeutic strategies in these patients. The approach of the diet therapy in these patients must be to reach specific goals such as improving insulin resistance, metabolic and reproductive functions that will be possible through the design of low-calorie diet to achieve weight loss or maintaining a healthy weight, limit the intake of simple sugars and refined carbohydrates and intake foods with a low glycemic index, reduction of saturated and trans fatty acids and attention to possible deficiencies such as vitamin D, chromium and omega-3. Given the prevalence of overweight and obesity and insulin resistance, a relatively low reduction in weight, about 5%, can improve problems such as insulin resistance, high levels of androgens, reproductive system dysfunctions and fertility in these women.

摘要

多囊卵巢综合征(PCOS)是育龄女性的一种内分泌紊乱疾病,会导致生殖、激素和代谢异常。由于存在胰岛素抵抗,PCOS会增加患2型糖尿病、高血压、脂质紊乱、心血管疾病以及乳腺癌和子宫内膜癌等恶性肿瘤等慢性疾病的风险。该综合征的实际病因尚不清楚,但饮食习惯等环境因素在预防和治疗中起着重要作用,生活方式的改变是这些患者最重要的治疗策略。这些患者的饮食治疗方法必须是达到特定目标,如改善胰岛素抵抗、代谢和生殖功能,这可以通过设计低热量饮食以实现体重减轻或维持健康体重、限制单糖和精制碳水化合物的摄入并摄入低血糖指数的食物、减少饱和脂肪酸和反式脂肪酸以及关注可能的维生素D、铬和ω-3缺乏来实现。鉴于超重和肥胖以及胰岛素抵抗的普遍性,体重相对轻微下降约5%就能改善这些女性的胰岛素抵抗、雄激素水平升高、生殖系统功能障碍和生育能力等问题。

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