Williams S M, Noble W C
Department of Microbiology, Institute of Dermatology, London, UK.
J Appl Bacteriol. 1988 Jun;64(6):475-82. doi: 10.1111/j.1365-2672.1988.tb02438.x.
A study of plasmids in coryneform bacteria isolated from human sources is reported. Seventy of 269 strains possessed a total of 89 plasmids. These were shown to be of varying sizes and in some cases of varying structures by endonuclease restriction digest. In six of 20 strains antibiotic resistance was cured with loss of the plasmid. The diversity of plasmids is emphasized.
报道了一项对从人类源分离出的棒状杆菌中质粒的研究。269株菌株中有70株共拥有89个质粒。通过核酸内切酶限制性消化显示,这些质粒大小各异,在某些情况下结构也不同。20株菌株中有6株的抗生素抗性随着质粒的丢失而消除。强调了质粒的多样性。