Institute of Science and Technology Austria, Am Campus 1, 3400 Klosterneuburg, Austria.
Bernstein Center for Computational Neuroscience, Am Fassberg 17, 37077 Göttingen, Germany.
Nat Commun. 2017 May 4;8:15140. doi: 10.1038/ncomms15140.
In real-world applications, observations are often constrained to a small fraction of a system. Such spatial subsampling can be caused by the inaccessibility or the sheer size of the system, and cannot be overcome by longer sampling. Spatial subsampling can strongly bias inferences about a system's aggregated properties. To overcome the bias, we derive analytically a subsampling scaling framework that is applicable to different observables, including distributions of neuronal avalanches, of number of people infected during an epidemic outbreak, and of node degrees. We demonstrate how to infer the correct distributions of the underlying full system, how to apply it to distinguish critical from subcritical systems, and how to disentangle subsampling and finite size effects. Lastly, we apply subsampling scaling to neuronal avalanche models and to recordings from developing neural networks. We show that only mature, but not young networks follow power-law scaling, indicating self-organization to criticality during development.
在实际应用中,观测通常局限于系统的一小部分。这种空间抽样可以由系统的不可访问性或巨大的规模引起,并且不能通过更长的采样来克服。空间抽样会强烈影响对系统聚合性质的推断。为了克服这种偏差,我们推导出了一种适用于不同观测值的抽样比例框架的解析方法,包括神经元雪崩的分布、传染病爆发期间感染人数的分布和节点度的分布。我们演示了如何推断基础全系统的正确分布,如何应用它来区分临界系统和亚临界系统,以及如何区分抽样和有限尺寸效应。最后,我们将抽样比例应用于神经元雪崩模型和发育中的神经网络的记录。我们表明,只有成熟的网络,而不是年轻的网络遵循幂律分布,这表明在发育过程中自我组织到临界状态。