Ene E, Halbfaß P, Nentwich K, Sonne K, Roos M, Fodor S, Lehmkuhl L, Gietzen F, Barth S, Hamm K, Deneke T
Herz- und Gefäßklinik, Salzburger Leite 1, 97616, Bad Neustadt a. d. Saale, Deutschland.
Herzschrittmacherther Elektrophysiol. 2017 Jun;28(2):212-218. doi: 10.1007/s00399-017-0501-7. Epub 2017 May 9.
Ventricular tachycardias (VT) in patients with structural heart diseases have predominantly a scar-associated reentry mechanism so that substrate-based ablation approaches also have to be used in nearly all procedures. In many VT cases-especially in nonischemic cardiomyopathy (NICM) and arrhythmogenic right ventricular cardiomyopathy-a critical epicardial substrate can be identified as an essential component of the reentry circuit so that for the ablation-based modification of the substrate in these cases an epicardial approach is necessary. In cases of redo-VT ablation procedures in ischemic cardiomyopathy (after a previously endocardial ablation), an epicardial approach should also be considered. There are also cases in whom no endocardial substrate can be identified and an isolated epicardial substrate can be identified. Worldwide epicardial VT ablations are usually performed after gaining epicardial access using subxyphoidal puncture. The results of recent studies show a higher efficiency with stabilization of cardiac rhythm and reduction of recurrent VT episodes (about 70% event-free survival at the 2‑year follow-up) after endo-plus epicardial substrate modification. In electrical storm cases, an early epicardial VT ablation approach also appears to be relevant, especially in NICM. Epicardial instrumentation and ablation represents a complex procedure which should only be performed in experienced centers with cardiac surgery back-up. In these experienced centers, the complications rate is less than 5%.
患有结构性心脏病的患者发生的室性心动过速(VT)主要具有与瘢痕相关的折返机制,因此在几乎所有手术中都必须采用基于基质的消融方法。在许多室性心动过速病例中,尤其是在非缺血性心肌病(NICM)和致心律失常性右心室心肌病中,关键的心外膜基质可被确定为折返环路的重要组成部分,因此对于这些病例中基于消融的基质改良,心外膜途径是必要的。在缺血性心肌病的再次室性心动过速消融手术中(先前进行心内膜消融后),也应考虑采用心外膜途径。也有一些病例无法识别心内膜基质,但可识别孤立的心外膜基质。在全球范围内,心外膜室性心动过速消融通常在通过剑突下穿刺获得心外膜通路后进行。最近的研究结果表明,在心内膜加心外膜基质改良后,心律稳定且室性心动过速复发事件减少(2年随访时约70%无事件生存率),效率更高。在电风暴病例中,早期的心外膜室性心动过速消融方法似乎也很重要,尤其是在非缺血性心肌病中。心外膜器械操作和消融是一个复杂的手术,应仅在有心脏外科支持的经验丰富的中心进行。在这些经验丰富的中心,并发症发生率低于5%。