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Genetics and Sinus Node Dysfunction.
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Roles and mechanisms of natural drugs on sinus node dysfunction.
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Sinus node function after cardiac transplantation.
J Am Coll Cardiol. 1994 Nov 1;24(5):1334-41. doi: 10.1016/0735-1097(94)90117-1.
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Sinus node dysfunction after intraatrial lateral tunnel and extracardiac conduit fontan procedures.
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Modifications to the cavopulmonary anastomosis do not eliminate early sinus node dysfunction.
J Thorac Cardiovasc Surg. 2000 Nov;120(5):891-900. doi: 10.1067/mtc.2000.109708.
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Sinus node function after a systematically staged Fontan procedure.
Circulation. 1998 Nov 10;98(19 Suppl):II352-8; discussion II358-9.

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Ion Channels in the Heart.
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A novel mutation in the HCN4 gene causes symptomatic sinus bradycardia in Moroccan Jews.
J Cardiovasc Electrophysiol. 2010 Dec;21(12):1365-72. doi: 10.1111/j.1540-8167.2010.01844.x.
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Genetic Na+ channelopathies and sinus node dysfunction.
Prog Biophys Mol Biol. 2008 Oct-Nov;98(2-3):171-8. doi: 10.1016/j.pbiomolbio.2008.10.003. Epub 2008 Nov 5.
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Atrial fibrillation and Brugada syndrome.
J Am Coll Cardiol. 2008 Mar 25;51(12):1149-53. doi: 10.1016/j.jacc.2007.10.062.
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New insights into genetic causes of sinus node disease and atrial fibrillation.
J Cardiovasc Electrophysiol. 2008 May;19(5):516-8. doi: 10.1111/j.1540-8167.2007.01097.x. Epub 2008 Feb 21.
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X-linked nonsyndromic sinus node dysfunction and atrial fibrillation caused by emerin mutation.
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Mutation of an A-kinase-anchoring protein causes long-QT syndrome.
Proc Natl Acad Sci U S A. 2007 Dec 26;104(52):20990-5. doi: 10.1073/pnas.0710527105. Epub 2007 Dec 19.
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HCN4 provides a 'depolarization reserve' and is not required for heart rate acceleration in mice.
EMBO J. 2007 Oct 31;26(21):4423-32. doi: 10.1038/sj.emboj.7601868. Epub 2007 Oct 4.
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HCN2 and HCN4 isoforms self-assemble and co-assemble with equal preference to form functional pacemaker channels.
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