Gonthier Clémentine, Estellat Candice, Deneux-Tharaux Catherine, Blondel Béatrice, Alfaiate Toni, Schmitz Thomas, Oury Jean-François, Mandelbrot Laurent, Luton Dominique, Ravaud Philippe, Azria Elie
UMR1153 - Obstetrical, Perinatal and Pediatric Epidemiology (EPOPé research team), DHU Risks in Pregnancy, Paris Descartes University - INSERM, 53 Avenue de l'Observatoire, 75014, Paris, France.
Department of Obstetrics and Gynecology, Beaujon-Bichat Hospital, DHU Risks in Pregnancy, APHP, Paris Diderot University, 46 Rue Henri Huchard, 75018, Paris, France.
BMC Pregnancy Childbirth. 2017 May 16;17(1):126. doi: 10.1186/s12884-017-1310-z.
Maternal social deprivation is associated with an increased risk of adverse maternal and perinatal outcomes. Inadequate prenatal care utilization (PCU) is likely to be an important intermediate factor. The health care system in France provides essential health services to all pregnant women irrespective of their socioeconomic status. Our aim was to assess the association between maternal social deprivation and PCU.
The analysis was performed in the database of the multicenter prospective PreCARE cohort study. The population source consisted in all parturient women registered for delivery in 4 university hospital maternity units, Paris, France, from October 2010 to November 2011 (N = 10,419). This analysis selected women with singleton pregnancies that ended after 22 weeks of gestation (N = 9770). The associations between maternal deprivation (four variables first considered separately and then combined as a social deprivation index: social isolation, poor or insecure housing conditions, no work-related household income, and absence of standard health insurance) and inadequate PCU were tested through multivariate logistic regressions also adjusted for immigration characteristics and education level.
Attendance at prenatal care was poor for 23.3% of the study population. Crude relative risks and confidence intervals for inadequate PCU were 1.6 [1.5-1.8], 2.3 [2.1-2.6], and 3.1 [2.8-3.4], for women with a deprivation index of 1, 2, and 3, respectively, compared to women with deprivation index of 0. Each of the four deprivation variables was significantly associated with an increased risk of inadequate PCU. Because of the interaction observed between inadequate PCU and mother's country of birth, we stratified for the latter before the multivariate analysis. After adjustment for the potential confounders, this social gradient remained for women born in France and North Africa. The prevalence of inadequate PCU among women born in sub-Saharan Africa was 34.7%; the social gradient in this group was attenuated and no longer significant. Other factors independently associated with inadequate PCU were maternal age, recent immigration, and unplanned or unwanted pregnancy.
Social deprivation is independently associated with an increased risk of inadequate PCU. Recognition of risk factors is an important step in identifying barriers to PCU and developing measures to overcome them.
孕产妇社会剥夺与孕产妇及围产期不良结局风险增加相关。产前保健利用率不足可能是一个重要的中间因素。法国的医疗保健系统为所有孕妇提供基本医疗服务,无论其社会经济地位如何。我们的目的是评估孕产妇社会剥夺与产前保健利用率之间的关联。
分析在多中心前瞻性PreCARE队列研究的数据库中进行。人群来源包括2010年10月至2011年11月在法国巴黎4家大学医院产科登记分娩的所有产妇(N = 10419)。该分析选取了妊娠22周后结束的单胎妊娠妇女(N = 9770)。通过多因素逻辑回归检验孕产妇剥夺(四个变量先分别考虑,然后合并为社会剥夺指数:社会孤立、住房条件差或不安全、无工作相关家庭收入以及无标准医疗保险)与产前保健利用率不足之间的关联,并对移民特征和教育水平进行了调整。
研究人群中23.3%的人产前保健就诊情况较差。与剥夺指数为0的妇女相比,剥夺指数为1、2和3的妇女产前保健利用率不足的粗相对风险及置信区间分别为1.6 [1.5 - 1.8]、2.3 [2.1 - 2.6]和3.1 [2.8 - 3.4]。四个剥夺变量中的每一个都与产前保健利用率不足风险增加显著相关。由于观察到产前保健利用率不足与母亲出生国家之间存在相互作用,我们在多因素分析前按母亲出生国家进行了分层。在对潜在混杂因素进行调整后,法国和北非出生的女性中这种社会梯度仍然存在。撒哈拉以南非洲出生的女性产前保健利用率不足的患病率为34.7%;该组中的社会梯度减弱且不再显著。与产前保健利用率不足独立相关的其他因素包括产妇年龄、近期移民以及意外或非意愿妊娠。
社会剥夺与产前保健利用率不足风险增加独立相关。识别风险因素是确定产前保健障碍并制定克服这些障碍措施的重要一步。