蝎子蜇伤后肾病综合征
Nephrotic syndrome after scorpion sting.
作者信息
Boju Sangeetha Lakshmi, Mogili Hari Krishna Reddy, Ram R, Vishnubotla Siva Kumar
机构信息
Nephrology, Sri Venkateswara Institute of Medical Sciences, Tirupati, AP, India.
出版信息
CEN Case Rep. 2016 May;5(1):83-86. doi: 10.1007/s13730-015-0197-7. Epub 2015 Sep 29.
Scorpion venom is a water soluble, antigenic and heterogeneous mixture. The venom is composed of varying concentration of neurotoxin, cardiotoxin, nephrotoxin, haemolytic toxin, phosphodiesterase, phospholipases, hyaluronidases, glycosaminoglycans, histamine, serotonins, and tryptophan and cytokine releasers. The reported incidence of scorpion sting in India is 0.6 %. Scorpion sting resulting in acute renal failure has been reported in the past, but not the nephrotic syndrome. We report a patient of nephrotic syndrome after scorpion sting. The lacunae in the present knowledge linking scorpion sting venom with nephrotic syndrome would only be replete with publications of similar reports.
蝎毒是一种水溶性、具有抗原性的异质混合物。毒液由不同浓度的神经毒素、心脏毒素、肾毒素、溶血毒素、磷酸二酯酶、磷脂酶、透明质酸酶、糖胺聚糖、组胺、血清素、色氨酸和细胞因子释放剂组成。据报道，印度蝎蜇伤的发病率为0.6%。过去曾有蝎蜇伤导致急性肾衰竭的报道，但未出现肾病综合征的报道。我们报告一例蝎蜇伤后发生肾病综合征的患者。目前关于蝎蜇伤毒液与肾病综合征之间联系的知识空白，只有通过更多类似报告的发表才能填补。
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