血小板活化因子对异丙肾上腺素诱导的大鼠和豚鼠离体气管段舒张的影响。
Effect of paf-acether on isoprenaline-induced relaxation in isolated tracheal segments of rats and guinea pigs.
作者信息
Chand N, Diamantis W, Sofia R D
机构信息
Department of Pharmacology, Wallace Laboratories, Division of Carter-Wallace, Inc., Cranbury, NJ 08512.
出版信息
Eur J Pharmacol. 1988 Dec 6;158(1-2):135-7. doi: 10.1016/0014-2999(88)90262-2.
PMID:2851453
Abstract
Platelet activating factor (paf-acether) was found to contract rat and guinea pig tracheal segments. It does not cause down regulation of beta-adrenoceptor in guinea pig trachea. In addition, paf-contracted rat tracheal segments lose their ability to relax in response to isoprenaline.
摘要
血小板活化因子（PAF-乙酰醚）被发现可使大鼠和豚鼠的气管段收缩。它不会导致豚鼠气管中β-肾上腺素能受体下调。此外，PAF收缩的大鼠气管段失去了对异丙肾上腺素产生舒张反应的能力。
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