Gavali Abhijit S, Shelgaonkar Jayant, Bartakke Sandip
Department of Critical Care Medicine, Aditya Birla Memorial Hospital, Pune, Maharashtra, India.
Department of Hematology, Aditya Birla Memorial Hospital, Pune, Maharashtra, India.
Indian J Crit Care Med. 2017 Apr;21(4):226-228. doi: 10.4103/ijccm.IJCCM_27_16.
Here, we present an unusual occurrence of thrombotic thrombocytopenic purpura (TTP) in a case of dengue fever. Both the conditions are fatal and can result in significant mortality and morbidity if left untreated. In this case, as soon as, we diagnosed the patient as having TTP, we treated her with plasma exchange therapy, steroids, and monoclonal antibodies such as rituximab. The patient responded very well to the treatment and completely recovered from neurological symptoms and laboratory parameters also normalized. Hence, timely diagnosis and starting appropriate treatment immediately are key factors for successful outcome.
在此,我们报告1例登革热患者出现血栓性血小板减少性紫癜(TTP)这一罕见情况。这两种病症均具有致命性,若不治疗可导致显著的死亡率和发病率。在该病例中,一旦我们诊断患者患有TTP,便立即采用血浆置换疗法、类固醇以及利妥昔单抗等单克隆抗体对其进行治疗。患者对治疗反应良好,神经症状完全恢复,实验室指标也恢复正常。因此,及时诊断并立即开始适当治疗是取得成功治疗效果的关键因素。