Wiant D, Pursley J, Sintay B
Regional Cancer Center Moses Cone Health Systems, Greensboro, NC.
Med Phys. 2012 Jun;39(6Part3):3617-3618. doi: 10.1118/1.4734687.
To evaluate the ability of AlignRT (VisionRT Ltd., London, UK) to accurately position patients receiving whole breast or chestwall irradiation and the impact of AlignRT on portal image dose.
Twenty whole breast or chestwall cases set-up using AlignRT at our site were compared to a series of 20 similar patients set-up without the use of AlignRT over the same time span. All patients were set-up head first supine, on a Quest Breastboard (Qfix, Avondale,PA). The AlignRT patients were positioned with an AlignRT region of interest that encompassed the ipsa-lateral chest minus the breast tissue drawn on a surface created from the patient contour generated in treatment planning. Non-AlignRT patients were positioned using skin marks added in simulation. Positional accuracy was verified by qualitative evaluation of portal imaging on the first treatment day, then once weekly.
The percentage of port images that were deemed unacceptable by therapists or radiation oncologists (> 3 mm deviation from simulation position) was 7.5 +/- 8.1% for the AlignRT group (with a range of 0 - 15%). In 14 of the 20 cases, one or fewer port images were unacceptable over the entire treatment. For the non-AlignRT group 20 +/- 14% (0-45%) of the images were unacceptable. In only 6 of the 20 cases one or fewer port images were found to be unacceptable over the course of treatment.
As judged by port images, AlignRT is able to provide a more accurate positioning of whole breast and chestwall patients, with a reduction in port dose and in set-up time, compared to the use of lasers and skin marks. The reduced number of rejected port images strongly suggests that AlignRT gives a more consistent, reproducible set-up on non- port days than skin marks alone.
评估AlignRT(英国伦敦VisionRT有限公司)对接受全乳或胸壁照射患者进行精确定位的能力,以及AlignRT对射野图像剂量的影响。
将我院使用AlignRT进行摆位的20例全乳或胸壁照射病例,与同一时期内未使用AlignRT进行摆位的20例类似患者进行比较。所有患者均头先进仰卧位,躺在Quest乳腺板(Qfix,宾夕法尼亚州阿冯代尔)上。使用AlignRT的患者通过一个感兴趣区域进行定位,该区域覆盖患侧胸部,但不包括在治疗计划中根据患者轮廓生成的表面上绘制的乳腺组织。未使用AlignRT的患者通过模拟时添加的皮肤标记进行摆位。在首次治疗日通过对射野图像进行定性评估来验证摆位准确性,之后每周验证一次。
AlignRT组中,治疗师或放射肿瘤学家认为不可接受的射野图像百分比(与模拟位置偏差>3 mm)为7.5±8.1%(范围为0 - 15%)。在20例病例中的14例中,整个治疗过程中不可接受的射野图像为1个或更少。对于未使用AlignRT的组,20±14%(0 - 45%)的图像不可接受。在20例病例中只有6例在整个治疗过程中发现不可接受的射野图像为1个或更少。
根据射野图像判断,与使用激光和皮肤标记相比,AlignRT能够为全乳和胸壁患者提供更精确的定位,同时减少射野剂量和摆位时间。被拒收的射野图像数量减少强烈表明,与单独使用皮肤标记相比,AlignRT在非射野日能提供更一致、可重复的摆位。