Response to Comment on "The Common R71H-G230A-R293Q Human Is a Null Allele".
作者信息
Patel Seema, Blaauboer Steven M, Tucker Heidi R, Mansouri Samira, Ruiz-Moreno Juan Sebastian, Hamann Lutz, Schumann Ralf R, Opitz Bastian, Jin Lei
机构信息
Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL 32610.
Department of Immunology and Microbial Disease, Albany Medical College, Albany, NY 12208; and.
出版信息
J Immunol. 2017 Jun 1;198(11):4185-4188. doi: 10.4049/jimmunol.1700322.
Abstract
摘要
相似文献
1
Response to Comment on "The Common R71H-G230A-R293Q Human Is a Null Allele".对《常见的R71H - G230A - R293Q人类基因是无效等位基因》评论的回应
J Immunol. 2017 Jun 1;198(11):4185-4188. doi: 10.4049/jimmunol.1700322.
2
Comment on "The Common R71H-G230A-R293Q Human Is a Null Allele".关于《常见的R71H - G230A - R293Q人类基因是无效等位基因》的评论
J Immunol. 2017 Jun 1;198(11):4183-4185. doi: 10.4049/jimmunol.1700294.
3
The Common R71H-G230A-R293Q Human TMEM173 Is a Null Allele.常见的R71H-G230A-R293Q人类TMEM173是一个无效等位基因。
J Immunol. 2017 Jan 15;198(2):776-787. doi: 10.4049/jimmunol.1601585. Epub 2016 Dec 7.
4
Correction: The Common R71H-G230A-R293Q Human Is a Null Allele.更正：常见的R71H-G230A-R293Q人类等位基因是无效等位基因。
J Immunol. 2017 Jun 1;198(11):4547. doi: 10.4049/jimmunol.1700477.
5
TMEM173 variants and potential importance to human biology and disease.TMEM173 变体及其对人类生物学和疾病的潜在重要性。
Genes Immun. 2019 Jan;20(1):82-89. doi: 10.1038/s41435-018-0029-9. Epub 2018 May 1.
6
The common alleles rescue CD4 T cellpenia, restore T-regs, and prevent inflammatory disease in mice.常见等位基因可挽救小鼠的CD4 T细胞减少症，恢复调节性T细胞，并预防炎症性疾病。
bioRxiv. 2024 Jun 17:2023.10.05.561109. doi: 10.1101/2023.10.05.561109.
7
Multiple Homozygous Variants in the STING-Encoding Gene in HIV Long-Term Nonprogressors.HIV 长期非进展者中 STING 编码基因的多个纯合变体。
J Immunol. 2018 May 15;200(10):3372-3382. doi: 10.4049/jimmunol.1701284. Epub 2018 Apr 9.
8
Single nucleotide polymorphisms of human STING can affect innate immune response to cyclic dinucleotides.人类 STING 的单核苷酸多态性可以影响对环状二核苷酸的先天免疫反应。
PLoS One. 2013 Oct 21;8(10):e77846. doi: 10.1371/journal.pone.0077846. eCollection 2013.
9
The common H232 STING allele shows impaired activities in DNA sensing, susceptibility to viral infection, and in monocyte cell function, while the HAQ variant possesses wild-type properties.常见的 H232STING 等位基因在 DNA 感应、易感性病毒感染以及单核细胞功能方面表现出活性受损，而 HAQ 变体则具有野生型特性。
Sci Rep. 2023 Nov 9;13(1):19541. doi: 10.1038/s41598-023-46830-5.
10
Sequence analysis of TMEM173 exon 5 in patients with systemic autoimmune diseases.系统性自身免疫性疾病患者TMEM173基因第5外显子的序列分析。
Autoimmunity. 2016;49(1):12-6. doi: 10.3109/08916934.2015.1113404. Epub 2015 Nov 22.
引用本文的文献
1
The common alleles rescue CD4 T cellpenia, restore T-regs, and prevent ) inflammatory disease in mice.常见的等位基因可挽救 CD4 T 细胞减少，恢复 T 调节细胞，并预防炎症性疾病在小鼠中发生。
Elife. 2024 Sep 18;13:RP96790. doi: 10.7554/eLife.96790.
2
Structural Evaluations of a Selective Human STING Agonist and Its Use in Macrophage Immunotherapies.一种选择性人源STING激动剂的结构评估及其在巨噬细胞免疫疗法中的应用
ACS Med Chem Lett. 2024 Apr 12;15(5):653-658. doi: 10.1021/acsmedchemlett.4c00048. eCollection 2024 May 9.
3
The common H232 STING allele shows impaired activities in DNA sensing, susceptibility to viral infection, and in monocyte cell function, while the HAQ variant possesses wild-type properties.常见的 H232STING 等位基因在 DNA 感应、易感性病毒感染以及单核细胞功能方面表现出活性受损，而 HAQ 变体则具有野生型特性。
Sci Rep. 2023 Nov 9;13(1):19541. doi: 10.1038/s41598-023-46830-5.
4
The common alleles rescue CD4 T cellpenia, restore T-regs, and prevent inflammatory disease in mice.常见等位基因可挽救小鼠的CD4 T细胞减少症，恢复调节性T细胞，并预防炎症性疾病。
bioRxiv. 2024 Jun 17:2023.10.05.561109. doi: 10.1101/2023.10.05.561109.
5
MPYS Modulates Fatty Acid Metabolism and Immune Tolerance at Homeostasis Independent of Type I IFNs.MPYS 独立于 I 型 IFNs 调节脂肪酸代谢和免疫耐受的稳态。
J Immunol. 2022 Dec 1;209(11):2114-2132. doi: 10.4049/jimmunol.2200158.
6
Association of homozygous variants of STING1 with outcome in human cervical cancer.STING1 基因纯合变体与宫颈癌患者预后的相关性。
Cancer Sci. 2021 Jan;112(1):61-71. doi: 10.1111/cas.14680. Epub 2020 Nov 20.
7
The Age of Cyclic Dinucleotide Vaccine Adjuvants.环二核苷酸疫苗佐剂时代。
Vaccines (Basel). 2020 Aug 13;8(3):453. doi: 10.3390/vaccines8030453.
8
Self-assembled cGAMP-STINGΔTM signaling complex as a bioinspired platform for cGAMP delivery.自组装 cGAMP-STINGΔTM 信号复合物作为 cGAMP 递送的仿生平台。
Sci Adv. 2020 Jun 12;6(24):eaba7589. doi: 10.1126/sciadv.aba7589. eCollection 2020 Jun.
9
TMEM173 variants and potential importance to human biology and disease.TMEM173 变体及其对人类生物学和疾病的潜在重要性。
Genes Immun. 2019 Jan;20(1):82-89. doi: 10.1038/s41435-018-0029-9. Epub 2018 May 1.
本文引用的文献
1
Comment on "The Common R71H-G230A-R293Q Human Is a Null Allele".关于《常见的R71H - G230A - R293Q人类基因是无效等位基因》的评论
J Immunol. 2017 Jun 1;198(11):4183-4185. doi: 10.4049/jimmunol.1700294.
2
The Common R71H-G230A-R293Q Human TMEM173 Is a Null Allele.常见的R71H-G230A-R293Q人类TMEM173是一个无效等位基因。
J Immunol. 2017 Jan 15;198(2):776-787. doi: 10.4049/jimmunol.1601585. Epub 2016 Dec 7.
3
Direct Activation of STING in the Tumor Microenvironment Leads to Potent and Systemic Tumor Regression and Immunity.肿瘤微环境中STING的直接激活导致强效且全身性的肿瘤消退和免疫。
Cell Rep. 2015 May 19;11(7):1018-30. doi: 10.1016/j.celrep.2015.04.031. Epub 2015 May 7.
4
STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade.含STING激动剂的癌症疫苗可治愈对PD-1阻断疗法耐药的已形成肿瘤。
Sci Transl Med. 2015 Apr 15;7(283):283ra52. doi: 10.1126/scitranslmed.aaa4306.
5
Single nucleotide polymorphisms of human STING can affect innate immune response to cyclic dinucleotides.人类 STING 的单核苷酸多态性可以影响对环状二核苷酸的先天免疫反应。
PLoS One. 2013 Oct 21;8(10):e77846. doi: 10.1371/journal.pone.0077846. eCollection 2013.
6
Structure-function analysis of STING activation by c[G(2',5')pA(3',5')p] and targeting by antiviral DMXAA.环状二核苷酸 c[G(2',5')pA(3',5')p] 对 STING 的激活及抗病毒 DMXAA 的靶向作用的结构-功能分析。
Cell. 2013 Aug 15;154(4):748-62. doi: 10.1016/j.cell.2013.07.023. Epub 2013 Aug 1.
7
The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING.先天免疫 DNA 传感器 cGAS 产生一种非经典的环二核苷酸，激活人类 STING。
Cell Rep. 2013 May 30;3(5):1355-61. doi: 10.1016/j.celrep.2013.05.009. Epub 2013 May 23.
8
Cyclic GMP-AMP synthase is a cytosolic DNA sensor that activates the type I interferon pathway.环鸟苷酸-腺苷酸合酶是一种胞质 DNA 传感器，可激活 I 型干扰素途径。
Science. 2013 Feb 15;339(6121):786-91. doi: 10.1126/science.1232458. Epub 2012 Dec 20.
9
Cyclic GMP-AMP is an endogenous second messenger in innate immune signaling by cytosolic DNA.环鸟苷酸-腺苷酸是细胞质 DNA 固有免疫信号转导中的内源性第二信使。
Science. 2013 Feb 15;339(6121):826-30. doi: 10.1126/science.1229963. Epub 2012 Dec 20.
10
Genome-wide genetic associations with IFNγ response to smallpox vaccine.全基因组遗传关联与天花疫苗对 IFNγ 的反应。
Hum Genet. 2012 Sep;131(9):1433-51. doi: 10.1007/s00439-012-1179-x. Epub 2012 Jun 3.
Zotero 插件