Cheng Dan-Dan, He Cong, Ai Hong-Hui, Huang Ying, Lu Nong-Hua
Department of Gastroenterology, The First Affiliated Hospital of Nanchang UniversityNanchang, China.
Department of Orthopaedics, The Yugan County People's HospitalYugan, China.
Front Microbiol. 2017 May 10;8:743. doi: 10.3389/fmicb.2017.00743. eCollection 2017.
() which colonizes the stomach can cause a wide array of gastric disorders, including chronic gastritis, peptic ulcer, and gastric cancer. Recently, accumulating evidence has implicated infection in extragastrointestinal diseases such as cardiovascular diseases, neurological disorders, and metabolic diseases. At the same time, many scholars have noted the relationship between infection and non-alcoholic fatty liver disease (NAFLD). Despite the positive association between and NAFLD reported in some researches, there are opposite perspectives denying their relationship. Due to high prevalence, unclear etiology and difficult treatment of NAFLD, confirming the pathogenicity of . p infection in NAFLD will undoubtedly provide insights for novel treatment strategies for NAFLD. This paper will review the relationship between infection and NAFLD and the possible pathogenic mechanisms.
()定植于胃部可引发多种胃部疾病,包括慢性胃炎、消化性溃疡和胃癌。最近,越来越多的证据表明其感染与心血管疾病、神经疾病和代谢疾病等胃肠道外疾病有关。同时,许多学者也注意到()感染与非酒精性脂肪性肝病(NAFLD)之间的关系。尽管一些研究报道了()与NAFLD之间存在正相关,但也有相反的观点否认它们之间的关系。由于NAFLD患病率高、病因不明且治疗困难,证实()感染在NAFLD中的致病性无疑将为NAFLD的新治疗策略提供思路。本文将综述()感染与NAFLD之间的关系以及可能的致病机制。