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中东国家哮喘及相关症状的患病率。

The prevalence of asthma and related symptoms in Middle East countries.

作者信息

Alavinezhad Azam, Boskabady Mohammad Hossein

机构信息

Neurogeneeic Inflammation Research Centre, Mashhad University of Medical Sciences, Mashhad, Iran.

Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

Clin Respir J. 2018 Mar;12(3):865-877. doi: 10.1111/crj.12655. Epub 2017 Jun 12.

Abstract

OBJECTIVES

Asthma is a chronic inflammatory airway disease characterized by reversible airway constriction and airway hyperresponsiveness. Asthma is a worldwide problem and its prevalence varies among different parts of the world. There are insufficient data about the prevalence and risk factors of this disease in Middle East countries.

DATA SOURCE

The objective of this review article was to determine the prevalence of asthma in Middle East countries by searching EMBASE, Medline, Web of Science and Google Scholar for articles about asthma prevalence in children and adults in this region.

STUDY SELECTION

The prevalence of asthma in different countries and different cities of each country in the Middle East was reviewed in children and adults of both sexes. The possible risk factors for asthma in different areas were also reviewed from 1985 to 2012.

RESULTS

The highest asthma prevalence in children and adults was 35.4% in Tehran, Iran by ISAAC phase I and 15% in Kuwait by self-designed questionnaire and the lowest prevalence was 1% in Kermanshah, Iran by ISAAC and 2% in Tehran, Iran by ECRHS questionnaire, respectively. Most studies showed that the prevalence of this common disease declines with increasing age.

CONCLUSION

The data showed that the prevalence of asthma varies among different countries and even among different cities of the same country. The common risk factors for this disease were genetic predisposition, cigarette smoking, family history of asthma and allergic diseases.

摘要

目的

哮喘是一种慢性炎症性气道疾病,其特征为可逆性气道收缩和气道高反应性。哮喘是一个全球性问题,在世界不同地区其患病率有所不同。中东国家关于该疾病患病率及危险因素的数据不足。

数据来源

这篇综述文章的目的是通过检索EMBASE、Medline、科学引文索引和谷歌学术,查找有关该地区儿童和成人哮喘患病率的文章,以确定中东国家哮喘的患病率。

研究选择

对中东地区不同国家以及每个国家不同城市中儿童和成人的哮喘患病率进行了综述。还对1985年至2012年不同地区哮喘的可能危险因素进行了综述。

结果

根据国际儿童哮喘和过敏研究(ISAAC)第一阶段的数据,伊朗德黑兰儿童和成人的哮喘患病率最高,为35.4%;根据自行设计的问卷,科威特的哮喘患病率为15%。患病率最低的分别是,根据ISAAC研究,伊朗克尔曼沙赫的哮喘患病率为1%;根据欧洲社区呼吸健康调查(ECRHS)问卷,伊朗德黑兰的哮喘患病率为2%。大多数研究表明,这种常见疾病的患病率随年龄增长而下降。

结论

数据显示,哮喘患病率在不同国家甚至同一国家的不同城市之间存在差异。该疾病的常见危险因素包括遗传易感性、吸烟、哮喘家族史和过敏性疾病。

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