He Jin-Peng, Shao Jing Fan, Hao Yun
1 Department of Pediatric Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Qiaokou District, Wuhan City, Hubei Province, China.
2 Department of Radiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Qiaokou District, Wuhan City, Hubei Province, China.
J Int Med Res. 2017 Jun;45(3):1190-1199. doi: 10.1177/0300060517706801. Epub 2017 May 28.
Objective Various methods are applied in the clinical treatment of idiopathic clubfoot. The purpose of this meta-analysis was to evaluate the efficacy of different conservative treatments. Methods Studies were pooled and odds ratio (ORs) with corresponding confidence intervals were calculated for evaluation of the results, relapses, and requirement for major surgery. Results A final analysis of 1435 patients from 9 eligible studies was performed. The combined OR indicated that significantly more fair and poor results were achieved and that major surgery was required significantly more often when using non-Ponseti's methods (OR = 3.33 and OR = 7.32, respectively), but no significant difference was detected in the occurrence of relapse (OR = 1.34). Pooled OR evaluation showed a significantly higher rate of fair and poor results, relapse, and requirement for major surgery when using Kite's method than when using Ponseti's method (OR = 3.93, OR = 2.53, and OR = 3.19, respectively), but no significant difference was detected between the French method and Ponseti's method (OR = 3.01, OR = 0.72, and OR = 1.26, respectively). Conclusions This meta-analysis indicates that Ponseti's method is safe and efficient for conservative treatment of clubfoot and decreases the number of surgical interventions required. It is recommended as the first-choice conservative treatment for idiopathic clubfoot.
目的 特发性马蹄内翻足的临床治疗方法多样。本荟萃分析旨在评估不同保守治疗方法的疗效。方法 汇总各项研究,计算比值比(OR)及相应的置信区间,以评估治疗结果、复发情况及大手术需求。结果 对9项符合条件的研究中的1435例患者进行了最终分析。合并OR表明,采用非庞塞蒂方法时,治疗结果为一般及较差的情况显著更多,且大手术需求也显著更频繁(OR分别为3.33和7.32),但复发率无显著差异(OR = 1.34)。汇总OR评估显示,与庞塞蒂方法相比,采用基特方法时,治疗结果为一般及较差的比率、复发率及大手术需求均显著更高(OR分别为3.93、2.53和3.19),但法国方法与庞塞蒂方法之间无显著差异(OR分别为3.01、0.72和1.26)。结论 本荟萃分析表明,庞塞蒂方法对马蹄内翻足的保守治疗安全有效,可减少所需的手术干预次数。推荐将其作为特发性马蹄内翻足的首选保守治疗方法。