免疫比浊法测定干血斑中A群链球菌抗链球菌溶血素O滴度（ASOT）：一种新检测方法的验证方法
Immuno-nephelometric determination of group streptococcal anti-streptolysin O titres (ASOT) from dried blood spots: Method for validating a new assay.
作者信息
Joseph John, Kent Neil, Bowen Asha, Hart Julie, Sheel Meru, Wardrop Robert, Abbs Sam, Bazely Scott, Rybak Monika
机构信息
PathWest Laboratory Medicine, QE2 Medical Centre Redevelopment, Australia.
PathWest Laboratory Medicine, QE2 Medical Centre Redevelopment, Australia.
出版信息
J Immunol Methods. 2017 Sep;448:59-65. doi: 10.1016/j.jim.2017.05.009. Epub 2017 May 26.
This study was designed to determine the sensitivity and reproducibility of recovering anti-streptolysin O titres (ASOT) from dried blood spot (DBS) samples, a methodologic subcomponent of the penicillin pharmacokinetic studies in children receiving secondary prophylaxis with intramuscular benzathine penicillin for acute rheumatic fever.
本研究旨在确定从干血斑（DBS）样本中恢复抗链球菌溶血素O滴度（ASOT）的敏感性和可重复性，这是在接受苄星青霉素肌内注射进行急性风湿热二级预防的儿童中开展青霉素药代动力学研究的一个方法学子部分。
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