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减重手术治疗假性脑瘤:病例报告及文献综述

Bariatric surgery as a treatment for pseudotumor cerebri: case study and narrative review of the literature.

作者信息

Cazzo Everton, Gestic Martinho Antonio, Utrini Murillo Pimentel, Mendonça Chaim Felipe David, Mendonça Chaim Fábio Henrique, Cândido Elaine Cristina, da Silveira Jarolavsky Luciana Bueno, de Almeida Ana Maria Neder, Pareja José Carlos, Chaim Elinton Adami

机构信息

MD, MSc, PhD. Assistant Professor, Department of Surgery, Faculdade de Ciências Médicas da Universidade Estadual de Campinas (FCM-UNICAMP), Campinas (SP), Brazil.

MD, MSc. Assistant Lecturer, Department of Surgery, Faculdade de Ciências Médicas da Universidade Estadual de Campinas (FCM-UNICAMP), Campinas (SP), Brazil.

出版信息

Sao Paulo Med J. 2017 May 29;136(2):182-187. doi: 10.1590/1516-3180.2016.0305060117. Print 2018 Mar-Apr.

Abstract

CONTEXT

Pseudotumor cerebri occurs when there is an increase in intracranial pressure without an underlying cause, usually leading to loss of vision. It is most commonly observed in obese women of child-bearing age.

CASE REPORT

A 46-year-old woman presented at our service with idiopathic intracranial hypertension that had been diagnosed two years earlier, which had led to chronic refractory headache and an estimated 30% loss of visual acuity, associated with bilateral papilledema. She presented partial improvement of the headache with acetazolamide, but the visual loss persisted. Her intracranial pressure was 34 cmH2O. She presented a body mass index of 39.5 kg/m2, also associated with high blood pressure. Computed tomography of the cranium with endovenous contrast did not show any abnormalities. She underwent Roux-en-Y gastric bypass with uneventful postoperative evolution. One month following surgery, she presented a 24% excess weight loss. An ophthalmological examination revealed absence of visual loss and remission of the papilledema. There were no new episodes of headache following the surgery. There was also complete resolution of high blood pressure. The intracranial pressure decreased to 24 cmH2O, six months after the surgery.

CONCLUSION

Although the condition is usually associated with obesity, there are few reports of bariatric surgery among individuals with pseudotumor cerebri. In cases studied previously, there was high prevalence of resolution or improvement of the disease following bariatric surgery. There is no consensus regarding which technique is preferable. Thus, further research is necessary in order to establish a specific algorithm.

摘要

背景

假性脑瘤是指在没有潜在病因的情况下颅内压升高,通常会导致视力丧失。最常见于育龄肥胖女性。

病例报告

一名46岁女性因特发性颅内高压前来我院就诊,该病两年前已确诊,导致慢性难治性头痛,估计视力丧失30%,伴有双侧视乳头水肿。她服用乙酰唑胺后头痛有部分改善,但视力丧失仍持续存在。她的颅内压为34 cmH₂O。她的体重指数为39.5 kg/m²,还伴有高血压。头颅增强CT未显示任何异常。她接受了Roux-en-Y胃旁路手术,术后恢复顺利。术后一个月,她的体重减轻了24%。眼科检查显示视力丧失消失,视乳头水肿消退。术后未再出现头痛发作。高血压也完全缓解。术后六个月,颅内压降至24 cmH₂O。

结论

虽然该病通常与肥胖有关,但关于假性脑瘤患者接受减肥手术的报道很少。在先前研究的病例中,减肥手术后疾病缓解或改善的发生率很高。关于哪种技术更可取尚无共识。因此,有必要进一步研究以建立特定的算法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7309/9879540/6e5cac982deb/1806-9460-spmj-136-02-182-gf1.jpg

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