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成人高盐渍蔬菜摄入量与高血压风险:一项12年随访研究。

High consumption of salt-fermented vegetables and hypertension risk in adults: a 12-year follow-up study.

作者信息

Song Hong Ji, Park Seon-Joo, Jang Dae Ja, Kwon Dae Young, Lee Hae-Jeung

机构信息

Department of Family Medicine, Hallym University Sacred Heart Hospital, Anyang-si, Korea.

Department of Food and Nutrition, Gachon University, Seongnam-si, Korea.

出版信息

Asia Pac J Clin Nutr. 2017;26(4):698-707. doi: 10.6133/apjcn.042016.13.

Abstract

BACKGROUND AND OBJECTIVES

The aim of this study was to investigate the causal relationship between high consumption of salt-fermented vegetables and hypertension risk in adults.

METHODS AND STUDY DESIGN

Data came from the Korean Genome and Epidemiology Study, an ongoing community-based cohort study that began in 2001. In the final analysis, a total of 5,932 participants (men=2,822, women=3,110) was included. Daily energy, nutrient, and major salt-fermented vegetables for Korean (kimchi) intakes were assessed using a semi-quantitative food frequency questionnaire. Relative risks and 95% CIs associated with kimchi intake by gender and body mass index (BMI) were estimated using the multivariate Cox proportional hazards regression model.

RESULTS

Out of the 5,932 participants, 1,798 (905 men, 893 women) developed hypertension during the 12-year follow-up period. A significant difference in baseline BMI was shown between the non-hypertension and hypertension groups. There was no significant difference with regard to the risk of developing hypertension across quintiles for total kimchi intake and quartile or quartiles for specific kimchi intake in multivariate models by gender and baseline BMI. The trend for increased risk of hypertension according to increasing quartile of watery kimchi intake was significant for obese men in the multivariate model (p<0.05).

CONCLUSION

High consumption of salt-fermented vegetables was not shown to be associated with increased risk of hypertension. The trend for increased risk of hypertension according to increasing quartile of watery kimchi intake was significant only in obese men.

摘要

背景与目的

本研究旨在调查成年人高盐渍蔬菜摄入量与高血压风险之间的因果关系。

方法与研究设计

数据来自韩国基因组与流行病学研究,这是一项始于2001年的正在进行的基于社区的队列研究。在最终分析中,共纳入了5932名参与者(男性=2822名,女性=3110名)。使用半定量食物频率问卷评估韩国人(泡菜)的每日能量、营养素和主要盐渍蔬菜摄入量。使用多变量Cox比例风险回归模型估计按性别和体重指数(BMI)划分的泡菜摄入量相关的相对风险和95%置信区间。

结果

在5932名参与者中,1798人(905名男性,893名女性)在12年的随访期内患上了高血压。非高血压组和高血压组之间的基线BMI存在显著差异。在按性别和基线BMI划分的多变量模型中,泡菜总摄入量的五分位数以及特定泡菜摄入量的四分位数或四分位数之间,患高血压的风险没有显著差异。在多变量模型中,对于肥胖男性,随着水萝卜泡菜摄入量四分位数的增加,高血压风险增加的趋势具有显著性(p<0.05)。

结论

未显示高盐渍蔬菜摄入量与高血压风险增加有关。仅在肥胖男性中,随着水萝卜泡菜摄入量四分位数的增加,高血压风险增加的趋势具有显著性。

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