Danforth J, Ports T A
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Data from the BHAT and the Norwegian timolol trail indicate that beta-blocking agents may provide significant benefit for the post-MI patient--regardless of the location of the infarct or the presence or absence of symptoms (ventricular arrhythmias) or risk factors (heart failure). Despite the lack of data, there is general agreement that beta blockers should be continued for at least 1 to 2 years after infarction in patients who are otherwise asymptomatic, and that these drugs should be continued indefinitely in post-MI patients with angina or hypertension who have no contraindications to beta blockers.
来自β-阻滞剂心脏预防试验(BHAT)和挪威噻吗洛尔试验的数据表明,β-阻滞剂可能为心肌梗死后患者带来显著益处,无论梗死部位如何,也无论是否存在症状(室性心律失常)或危险因素(心力衰竭)。尽管缺乏数据,但人们普遍认为,对于无症状的患者,心肌梗死后应至少持续使用β-阻滞剂1至2年;对于没有β-阻滞剂使用禁忌证的心肌梗死后心绞痛或高血压患者,这些药物应无限期持续使用。