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Roux-en-Y 胃旁路术失败后转为胆胰分流十二指肠转流术:9 个病例系列的结果。

Conversion of failed Roux-en-Y gastric bypass to biliopancreatic diversion with duodenal switch: outcomes of 9 case series.

机构信息

Department of Surgery, Abington - Jefferson Health - Institute of Bariatric and Metabolic Surgery, Abington, Pennsylvania.

Department of Surgery, Abington - Jefferson Health - Institute of Bariatric and Metabolic Surgery, Abington, Pennsylvania.

出版信息

Surg Obes Relat Dis. 2017 Aug;13(8):1272-1277. doi: 10.1016/j.soard.2017.04.021. Epub 2017 Apr 26.

Abstract

INTRODUCTION

Weight regain after Roux-en-Y gastric bypass (RYGB) is a frustrating long-term complication in some patients. Revision of RYGB to biliopancreatic diversion with duodenal switch (BPD-DS) is an appealing option. There is a paucity of information in literature regarding this type of conversion.

SETTING

Regional referral center and teaching hospital, Pennsylvania, United States; nonprofit.

METHODS

Between 2013 and 2016, a retrospective chart review was performed on all our revision cases. Patients who underwent conversion from RYGB to BPD-DS were selected and analyzed.

RESULTS

Conversion from RYGB to BPD-DS was performed on 9 patients (8 females, 1 male; mean age: 49.2±7.6 [36-61] years). The mean body mass index (BMI) before the initial RYGB was 54.2±14.2 (36.2-79) kg/m. The lowest mean BMI reached before conversion was 33.9±6.2 (27.9-43.3) kg/m before it increased to 45.6±8.7 (28.8-60.2) corresponding to excess weight loss (EWL) of 33.1%±17.7% (10.6%-68.1%), before conversion. The average operative time was 402.6±65.8 (328-515) minutes for 1-stage conversions. No morbidities, reoperation, or readmission over 30 days postoperatively were reported. No leaks or mortalities were identified. The mean duration of follow-up postconversion is 16.3±13.6 (3-42) months. After conversion surgery, the mean BMI was 35.8±8.2 (27.6-49.5) kg/m, while mean EWL loss was 64.1%±18.8% (45.9%-88.7%). The BMI of the cohort decreased by a mean of 9.8±5.1 (0.5-16.8) and the EWL increased by 31%±23.1% (4%-76.6%).

CONCLUSION

Our results indicate that conversion of failed RYGB to BPD-DS is laparoscopically or robotically safe and effective. A large cohort study with long-term follow-up is necessary to further assess the safety and efficacy of this method.

摘要

简介

在某些患者中,胃旁路术后(RYGB)后的体重反弹是一种令人沮丧的长期并发症。将 RYGB 修正为胆胰分流加十二指肠转位术(BPD-DS)是一种有吸引力的选择。但是,文献中关于这种转换的信息很少。

地点

美国宾夕法尼亚州的地区转诊中心和教学医院;非营利组织。

方法

2013 年至 2016 年,我们对所有的修正病例进行了回顾性图表审查。选择并分析了从 RYGB 转换为 BPD-DS 的患者。

结果

对 9 名患者(8 名女性,1 名男性;平均年龄:49.2±7.6[36-61]岁)进行了 RYGB 到 BPD-DS 的转换。初次 RYGB 前的平均体重指数(BMI)为 54.2±14.2(36.2-79)kg/m。在转换前,最低平均 BMI 达到 33.9±6.2(27.9-43.3)kg/m,之后增加到 45.6±8.7(28.8-60.2)kg/m,相应的超重减轻率(EWL)为 33.1%±17.7%(10.6%-68.1%)。1 期转换的平均手术时间为 402.6±65.8(328-515)分钟。术后 30 天内无任何并发症、再次手术或再次入院。未发现漏诊或死亡。转换手术后的平均随访时间为 16.3±13.6(3-42)个月。转换手术后,平均 BMI 为 35.8±8.2(27.6-49.5)kg/m,平均 EWL 丢失率为 64.1%±18.8%(45.9%-88.7%)。该队列的 BMI 平均下降了 9.8±5.1(0.5-16.8),EWL 增加了 31%±23.1%(4%-76.6%)。

结论

我们的结果表明,将失败的 RYGB 转换为 BPD-DS 是安全有效的,腹腔镜或机器人手术均适用。需要进行更大的队列研究和长期随访,以进一步评估这种方法的安全性和有效性。

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