执行任务期间前额叶激活在幼儿期逐渐显现：来自功能近红外光谱的证据。
Prefrontal Activation During Executive Tasks Emerges Over Early Childhood: Evidence From Functional Near Infrared Spectroscopy.
作者信息
Smith Elizabeth, Anderson Afrouz, Thurm Audrey, Shaw Philip, Maeda Mika, Chowdhry Fatima, Chernomordik Victor, Gandjbakhche Amir
机构信息
a Department of Human Development , National Institute of Child Health and Human Development , Bethesda , Maryland.
b Pediatrics and Developmental Neuroscience Branch, National Institute of Mental Health , Bethesda , Maryland.
出版信息
Dev Neuropsychol. 2017;42(4):253-264. doi: 10.1080/87565641.2017.1318391. Epub 2017 Jun 16.
Abstract
Functional Near Infrared Spectroscopy (fNIRS) is a brain imaging technique that is well-suited for use in young children, making it particularly useful for investigating the neural bases of the development of executive functions. In the present study, children (ages 4-10) underwent fNIRS while completing response inhibition and working memory tasks. While both tasks were associated with increases in oxyhemoglobin and decreases in deoxyhemoglobin, we found that strength of activation increased with age and with improvements in task performance. These findings support the relation between emerging executive functions and maturation of the prefrontal cortex.
摘要
功能近红外光谱技术（fNIRS）是一种脑成像技术，非常适合用于幼儿，这使得它在研究执行功能发展的神经基础方面特别有用。在本研究中，4至10岁的儿童在完成反应抑制和工作记忆任务时接受了功能近红外光谱技术检测。虽然这两项任务都与氧合血红蛋白增加和脱氧血红蛋白减少有关，但我们发现激活强度随着年龄增长和任务表现的改善而增加。这些发现支持了新兴执行功能与前额叶皮质成熟之间的关系。
相似文献
1
Prefrontal Activation During Executive Tasks Emerges Over Early Childhood: Evidence From Functional Near Infrared Spectroscopy.
Dev Neuropsychol. 2017;42(4):253-264. doi: 10.1080/87565641.2017.1318391. Epub 2017 Jun 16.
2
Functional Near-Infrared Spectroscopy Evidence for Development of Prefrontal Engagement in Working Memory in Early Through Middle Childhood.
Cereb Cortex. 2016 Jun;26(6):2790-9. doi: 10.1093/cercor/bhv139. Epub 2015 Jun 26.
3
Influences of age, mental workload, and flight experience on cognitive performance and prefrontal activity in private pilots: a fNIRS study.
Sci Rep. 2019 May 22;9(1):7688. doi: 10.1038/s41598-019-44082-w.
4
Mental workload and neural efficiency quantified in the prefrontal cortex using fNIRS.
Sci Rep. 2017 Jul 12;7(1):5222. doi: 10.1038/s41598-017-05378-x.
5
Executive n-back tasks for the neuropsychological assessment of working memory.
Behav Brain Res. 2015 Oct 1;292:167-73. doi: 10.1016/j.bbr.2015.06.002. Epub 2015 Jun 9.
6
Differences in prefrontal cortex activity based on difficulty in a working memory task using near-infrared spectroscopy.
Behav Brain Res. 2020 Aug 17;392:112722. doi: 10.1016/j.bbr.2020.112722. Epub 2020 May 30.
7
Moderate-to-vigorous physical activity, executive functions and prefrontal brain oxygenation in children: A functional near-infrared spectroscopy study.
J Sports Sci. 2018 Mar;36(6):630-636. doi: 10.1080/02640414.2017.1326619. Epub 2017 May 24.
8
Age-related decline in visuo-spatial working memory is reflected by dorsolateral prefrontal activation and cognitive capabilities.
Behav Brain Res. 2021 Feb 1;398:112981. doi: 10.1016/j.bbr.2020.112981. Epub 2020 Nov 2.
9
Working and short-term memory in children with ADHD: an examination of prefrontal cortical functioning using functional Near-Infrared Spectroscopy (fNIRS).
Child Neuropsychol. 2024 Apr;30(3):462-485. doi: 10.1080/09297049.2023.2213463. Epub 2023 May 18.
10
Relation between working memory performance and evoked cerebral blood oxygenation changes in the prefrontal cortex evaluated by quantitative time-resolved near-infrared spectroscopy.
Neurol Res. 2012 Mar;34(2):114-9. doi: 10.1179/1743132811Y.0000000066. Epub 2012 Jan 13.
引用本文的文献
1
Measuring neurodevelopment of inhibitory control in children using naturalistic virtual reality.
Sci Rep. 2025 Jul 24;15(1):26944. doi: 10.1038/s41598-025-10974-3.
2
Reduced recruitment of inhibitory control regions in very young children with ADHD during a modified Kiddie Continuous Performance Task: A fMRI study.
Cortex. 2025 Apr;185:153-169. doi: 10.1016/j.cortex.2024.11.025. Epub 2025 Feb 25.
3
Executive control of freestyle skiing aerials athletes in different training conditions.
Front Psychol. 2022 Sep 26;13:968651. doi: 10.3389/fpsyg.2022.968651. eCollection 2022.
4
Enhancing Chinese preschoolers' executive function mindfulness training: An fNIRS study.
Front Behav Neurosci. 2022 Aug 25;16:961797. doi: 10.3389/fnbeh.2022.961797. eCollection 2022.
5
Novel imaging technologies for genetic diagnoses in the inborn errors of metabolism.
J Transl Genet Genom. 2020;4:429-445. doi: 10.20517/jtgg.2020.09. Epub 2020 Nov 13.
6
Teacher-Rated Executive Functions, Gender and Relative Age: Independent and Interactive Effects on Observed Fundamental Motor Skills in Kindergarteners.
Front Psychol. 2022 Feb 22;13:848525. doi: 10.3389/fpsyg.2022.848525. eCollection 2022.
7
A Network Perspective on the Relationship between Screen Time, Executive Function, and Fundamental Motor Skills among Preschoolers.
Int J Environ Res Public Health. 2020 Nov 28;17(23):8861. doi: 10.3390/ijerph17238861.
8
DHEAS and Human Development: An Evolutionary Perspective.
Front Endocrinol (Lausanne). 2020 Mar 3;11:101. doi: 10.3389/fendo.2020.00101. eCollection 2020.
9
Neural substrates of early executive function development.
Dev Rev. 2019 Jun;52:42-62. doi: 10.1016/j.dr.2019.100866.
10
Neural activation within the prefrontal cortices during the goal-directed motor actions of children with hemiplegic cerebral palsy.
Neurophotonics. 2018 Jan;5(1):011021. doi: 10.1117/1.NPh.5.1.011021. Epub 2018 Mar 10.
本文引用的文献
1
The neural substrates of cognitive flexibility are related to individual differences in preschool irritability: A fNIRS investigation.
Dev Cogn Neurosci. 2017 Jun;25:138-144. doi: 10.1016/j.dcn.2016.07.002. Epub 2016 Aug 4.
2
Functional Near-Infrared Spectroscopy Evidence for Development of Prefrontal Engagement in Working Memory in Early Through Middle Childhood.
Cereb Cortex. 2016 Jun;26(6):2790-9. doi: 10.1093/cercor/bhv139. Epub 2015 Jun 26.
3
As Working Memory Grows: A Developmental Account of Neural Bases of Working Memory Capacity in 5- to 8-Year Old Children and Adults.
J Cogn Neurosci. 2015 Sep;27(9):1775-88. doi: 10.1162/jocn_a_00824. Epub 2015 May 11.
4
Modified Beer-Lambert law for blood flow.
Biomed Opt Express. 2014 Oct 28;5(11):4053-75. doi: 10.1364/BOE.5.004053. eCollection 2014 Nov 1.
5
Relationship between working memory performance and neural activation measured using near-infrared spectroscopy.
Brain Behav. 2014 Jul;4(4):544-51. doi: 10.1002/brb3.238. Epub 2014 May 24.
6
Sensitivity of fNIRS to cognitive state and load.
Front Hum Neurosci. 2014 Feb 20;8:76. doi: 10.3389/fnhum.2014.00076. eCollection 2014.
7
Developmental changes in frontal lobe function during a verbal fluency task: a multi-channel near-infrared spectroscopy study.
Brain Dev. 2014 Nov;36(10):844-52. doi: 10.1016/j.braindev.2014.01.002. Epub 2014 Feb 7.
8
Inhibition and the right inferior frontal cortex: one decade on.
Trends Cogn Sci. 2014 Apr;18(4):177-85. doi: 10.1016/j.tics.2013.12.003. Epub 2014 Jan 15.
9
Prefrontal cortex and executive function in young children: a review of NIRS studies.
Front Hum Neurosci. 2013 Dec 17;7:867. doi: 10.3389/fnhum.2013.00867.
10
Dynamic causal modeling of load-dependent modulation of effective connectivity within the verbal working memory network.
Hum Brain Mapp. 2014 Jul;35(7):3025-35. doi: 10.1002/hbm.22382. Epub 2013 Oct 18.
Zotero 插件