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撤回:趋化因子 Fractalkine/CX3CR1 信号通路在大鼠早期缺血性脑卒中后神经功能恢复中的作用。

RETRACTED: Role of fractalkine/CX3CR1 signaling pathway in the recovery of neurological function after early ischemic stroke in a rat model.

机构信息

Department of Neurology, The Second Hospital of Dalian Medical University, Dalian 116023, PR China.

Department of Neurology, The Second Hospital of Dalian Medical University, Dalian 116023, PR China.

出版信息

Life Sci. 2017 Sep 1;184:87-94. doi: 10.1016/j.lfs.2017.06.012. Epub 2017 Jun 15.

DOI:10.1016/j.lfs.2017.06.012
PMID:28624392
Abstract

This article has been retracted: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been retracted at the request of the authors and Editor-in-Chief. Concern was raised about the reliability of the Western blot results, as detailed here: https://pubpeer.com/publications/7BB8F6559AF31100A59484E5D97802; and here: https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249. In addition, a portion of Figure 5A, CA3 ‘Positive control’ group appears to contain image similarities with Figure 5A, CA1 ‘CX3CR1 inhibitor’ group. The journal requested that the corresponding author comment on these concerns and provide the raw data. However, the authors were not able to satisfactorily fulfill this request and therefore the Editor-in-Chief decided to retract the article.

摘要

本文已被撤回

请参阅 Elsevier 撤稿政策(http://www.elsevier.com/locate/withdrawalpolicy)。应作者和主编的要求撤回了本文。对 Western blot 结果的可靠性提出了质疑,详细内容如下:https://pubpeer.com/publications/7BB8F6559AF31100A59484E5D97802;以及此处:https://docs.google.com/spreadsheets/d/1r0MyIYpagBc58BRF9c3luWNlCX8VUvUuPyYYXzxWvgY/edit#gid=262337249。此外,图 5A 的 CA3“阳性对照”组的一部分似乎与图 5A 的 CA1“CX3CR1 抑制剂”组存在图像相似性。期刊要求通讯作者对这些问题发表评论并提供原始数据。但是,作者无法令人满意地满足这一要求,因此主编决定撤回该文章。

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