Pfeifer P, Bartsch C, Hemmer A, Reisch T
Hospital of Psychiatry Münsingen, Hunzigenallee 1, 3110 Münsingen, Switzerland; University Hospital of Psychiatry Bern, University of Bern, 3000, Bern 60, Switzerland.
Alfred-Wegener-Institute, Helmholtz-Center for Polar- und Marine Research, Am alten Hafen 26, 27515 Bremerhaven, Germany.
Drug Alcohol Depend. 2017 Sep 1;178:75-79. doi: 10.1016/j.drugalcdep.2017.05.009. Epub 2017 Jun 16.
Chronic and acute alcohol use are highly associated risk factors for suicides worldwide. Therefore, we examined suicide cases with and without alcohol use disorder (AUD) using data from the SNSF project "Suicide in Switzerland: A detailed national survey". Our investigations focus on correlations between acute and chronic alcohol use with reference to suicide and potential interactions with the methods of suicide.
We used data from the SNSF project in which all cases of registered completed suicide in Switzerland reported to any of the seven Swiss institutes of legal and forensic medicine between 2000 and 2010 were collected. We extracted cases that were tested for blood alcohol to use in our analysis. We compared clinical characteristics, blood alcohol concentrations, and methods of suicide in cases with and without AUD.
Out of 6497 cases, 2946 subjects were tested for acute alcohol use and included in our analysis. Of the latter, 366 (12.4%) persons had a medical history of AUD. Subjects with AUD significantly had higher blood alcohol concentrations and were more often in medical treatment before suicide. Drug intoxication as method of suicide was more frequent in cases with AUD compared to NAUD.
Overall, we found a high incidence of acute alcohol use at the time of death in chronic alcohol misusers (AUD). The five methods of suicide most commonly used in Switzerland differed considerably between individuals with and without AUD. Blood alcohol concentrations varied across different methods of suicide independently from the medical history in both groups.
在全球范围内,慢性和急性酒精使用都是与自杀高度相关的风险因素。因此,我们利用瑞士国家科学基金会项目“瑞士的自杀:一项详细的全国性调查”的数据,对有和没有酒精使用障碍(AUD)的自杀案例进行了研究。我们的调查重点是急性和慢性酒精使用与自杀之间的相关性,以及与自杀方法的潜在相互作用。
我们使用了瑞士国家科学基金会项目的数据,该项目收集了2000年至2010年间瑞士七所法律和法医学研究所报告的瑞士所有登记的自杀既遂案例。我们提取了进行血液酒精检测的案例用于分析。我们比较了有和没有酒精使用障碍的案例的临床特征、血液酒精浓度和自杀方法。
在6497个案例中,2946名受试者接受了急性酒精使用检测并纳入我们的分析。在后者中,366人(12.4%)有酒精使用障碍病史。有酒精使用障碍的受试者血液酒精浓度显著更高,并且在自杀前接受治疗的频率更高。与无酒精使用障碍者相比,有酒精使用障碍者中药物中毒作为自杀方法更为常见。
总体而言,我们发现在慢性酒精滥用者(有酒精使用障碍)死亡时急性酒精使用的发生率很高。在瑞士,有和没有酒精使用障碍的个体最常用的五种自杀方法有很大差异。两组中,不同自杀方法的血液酒精浓度各不相同,且与病史无关。