Newham James J, Presseau Justin, Heslop-Marshall Karen, Russell Sian, Ogunbayo Oladapo J, Netts Paul, Hanratty Barbara, Kaner Eileen
Institute of Health and Society, Newcastle University, Newcastle upon Tyne, UK.
Ottawa Hospital Research Institute, The Ottawa Hospital, General Campus, Ottawa, ON, Canada.
Int J Chron Obstruct Pulmon Dis. 2017 Jun 8;12:1705-1720. doi: 10.2147/COPD.S133317. eCollection 2017.
Self-management interventions (SMIs) are recommended for individuals with COPD to help monitor symptoms and optimize health-related quality of life (HRQOL). However, SMIs vary widely in content, delivery, and intensity, making it unclear which methods and techniques are associated with improved outcomes. This systematic review aimed to summarize the current evidence base surrounding the effectiveness of SMIs for improving HRQOL in people with COPD.
Systematic reviews that focused upon SMIs were eligible for inclusion. Intervention descriptions were coded for behavior change techniques (BCTs) that targeted self-management behaviors to address 1) symptoms, 2) physical activity, and 3) mental health. Meta-analyses and meta-regression were used to explore the association between health behaviors targeted by SMIs, the BCTs used, patient illness severity, and modes of delivery, with the impact on HRQOL and emergency department (ED) visits.
Data related to SMI content were extracted from 26 randomized controlled trials identified from 11 systematic reviews. Patients receiving SMIs reported improved HRQOL (standardized mean difference =-0.16; 95% confidence interval [CI] =-0.25, -0.07; =0.001) and made fewer ED visits (standardized mean difference =-0.13; 95% CI =-0.23, -0.03; =0.02) compared to patients who received usual care. Patients receiving SMIs targeting mental health alongside symptom management had greater improvement of HRQOL (Q=4.37; =0.04) and fewer ED visits (Q=5.95; =0.02) than patients receiving SMIs focused on symptom management alone. Within-group analyses showed that HRQOL was significantly improved in 1) studies with COPD patients with severe symptoms, 2) single-practitioner based SMIs but not SMIs delivered by a multidisciplinary team, 3) SMIs with multiple sessions but not single session SMIs, and 4) both individual- and group-based SMIs.
SMIs can be effective at improving HRQOL and reducing ED visits, with those targeting mental health being significantly more effective than those targeting symptom management alone.
对于慢性阻塞性肺疾病(COPD)患者,推荐采用自我管理干预措施(SMIs)来帮助监测症状并优化健康相关生活质量(HRQOL)。然而,SMIs在内容、实施方式和强度方面差异很大,这使得尚不清楚哪些方法和技术与改善结局相关。本系统评价旨在总结目前围绕SMIs对改善COPD患者HRQOL有效性的证据基础。
聚焦于SMIs的系统评价符合纳入标准。对干预描述进行编码,以确定针对自我管理行为的行为改变技术(BCTs),这些行为旨在解决以下三个方面:1)症状,2)身体活动,以及3)心理健康。采用荟萃分析和荟萃回归来探讨SMIs所针对的健康行为、所使用的BCTs、患者疾病严重程度和实施方式与对HRQOL和急诊就诊的影响之间的关联。
从11项系统评价中确定的26项随机对照试验中提取了与SMI内容相关的数据。与接受常规护理的患者相比,接受SMIs的患者报告HRQOL有所改善(标准化均数差=-0.16;95%置信区间[CI]=-0.25,-0.07;P=0.001),且急诊就诊次数减少(标准化均数差=-0.