猪源产气荚膜梭菌肠毒素纯化产物的肠道致病性
Enteropathogenicity of purified Clostridium perfringens enterotoxin in the pig.
作者信息
Popoff M R, Jestin A
出版信息
Am J Vet Res. 1985 Oct;46(10):2147-8.
PMID:2865919
Abstract
In an assay procedure, purified Clostridium perfringens enterotoxin induced the accumulation of fluid in the ileal loop of the axenic pig. The smallest amount of enterotoxin causing a positive response was 25 micrograms (1:32 titer by counterimmunoelectrophoresis [CIEP] ), and 100 micrograms (1:128 CIEP titer) caused a marked response. Possibly, diarrhea in pigs with 1:32 CIEP titer or more of enterotoxin in the feces may be associated with enterotoxigenic C perfringens.
摘要
在一项测定程序中，纯化的产气荚膜梭菌肠毒素在无菌猪的回肠袢中诱导了液体蓄积。引起阳性反应的肠毒素最小量为25微克（通过对流免疫电泳[CIEP]测定为1:32效价），100微克（CIEP效价为1:128）引起明显反应。粪便中CIEP效价为1:32或更高的肠毒素的猪出现腹泻可能与产肠毒素的产气荚膜梭菌有关。
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