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肿瘤学实践中的端口:每3个月用生理盐水封管以维护导管,初步报告。

Port in oncology practice: 3-monthly locking with normal saline for catheter maintenance, a preliminary report.

作者信息

Solinas Gianfranca, Platini Francesca, Trivellato Maurizio, Rigo Carla, Alabiso Oscar, Galetto Alessandra S

机构信息

Oncology Division, University Hospital "Maggiore della Carità", Novara - Italy.

Department of Translational Medicine, University of Eastern Piedmont, Novara - Italy.

出版信息

J Vasc Access. 2017 Jul 14;18(4):325-327. doi: 10.5301/jva.5000740. Epub 2017 Jun 20.

Abstract

INTRODUCTION

Patients with cancer need stable venous access using central vascular devices like central venous ports and peripherally inserted central catheters that can be used for a wide range of indications. Numerous flushing protocols exist including different frequencies for catheter locking to maintain catheter patency. The aim of this retrospective study was to evaluate the incidence of lumen occlusion of central venous ports in a group of adult cancer patients, adopting a policy of locking with normal saline every three months.

METHODS

This is a single-center retrospective observational study. During follow-up, we analyzed adult cancer patients who had undergone port insertion from January 1st, 2007 to August 31st, 2014. Flushing and locking were performed every three months with a syringe containing normal saline.

RESULTS

We collected data from 381 patients with ports inserted in subclavian vein (379 patients) and in the right jugular vein (2 patients). Locking was performed during 3-monthly follow-up visits. Median follow-up was 810 days (90-2700 days). Among 381 ports, 59 were removed; the reasons for removal were: end of use (45 cases), catheter rupture (9 cases), dislocation (3 cases) and catheter-related bloodstream infection (2 cases). We had no reports of lumen occlusion.

CONCLUSIONS

Our data suggest that locking ports with normal saline every three months is not associated with an increased risk of lumen occlusion.

摘要

引言

癌症患者需要使用中心静脉端口和外周静脉置入中心静脉导管等中心血管装置来建立稳定的静脉通路,这些装置可用于多种适应症。存在许多冲洗方案,包括不同的导管封管频率以维持导管通畅。本回顾性研究的目的是评估一组成年癌症患者中中心静脉端口管腔闭塞的发生率,采用每三个月用生理盐水封管的策略。

方法

这是一项单中心回顾性观察研究。在随访期间,我们分析了2007年1月1日至2014年8月31日期间接受端口置入的成年癌症患者。每三个月用装有生理盐水的注射器进行冲洗和封管。

结果

我们收集了381例在锁骨下静脉(379例患者)和右颈静脉(2例患者)置入端口的患者的数据。在每三个月的随访中进行封管。中位随访时间为810天(90 - 2700天)。在381个端口中,59个被拔除;拔除原因是:使用结束(45例)、导管破裂(9例)、移位(3例)和导管相关血流感染(2例)。我们没有管腔闭塞的报告。

结论

我们的数据表明,每三个月用生理盐水封管与管腔闭塞风险增加无关。

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